EMC6 (ER membrane protein complex subunit 6)

2018-07-01  

Identity

HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
RAB5IFL,TMEM93
FUSION GENES

Other Information

Locus ID:

NCBI: 83460
HGNC: 28430
Ensembl: ENSG00000127774

Variants:

dbSNP: 83460
ClinVar: 83460
TCGA: ENSG00000127774
COSMIC: EMC6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127774ENST00000248378Q9BV81
ENSG00000127774ENST00000397133Q9BV81

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
231829412013A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy.22
286481452017ER membrane protein complex subunit 6 (EMC6) is a novel tumor suppressor in gastric cancer.3
287422032017Expression levels and roles of EMC-6, Beclin1, and Rab5a in the cervical cancer.2
309825752019Ad5-EMC6 mediates antitumor activity in gastric cancer cells through the mitochondrial apoptosis pathway.0

Citation

Dessen P

EMC6 (ER membrane protein complex subunit 6)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57402/emc6