ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4)

2014-11-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
NPP4
FUSION GENES

Other Information

Locus ID:

NCBI: 22875
MIM: 617000
HGNC: 3359
Ensembl: ENSG00000001561

Variants:

dbSNP: 22875
ClinVar: 22875
TCGA: ENSG00000001561
COSMIC: ENPP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000001561ENST00000321037Q9Y6X5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Purine metabolismKEGGhsa00230
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
229958982012NPP4 is a procoagulant enzyme on the surface of vascular endothelium.10
243380102014Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke.8

Citation

Dessen P

ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62837/enpp4