| Nomenclature |
|---|
| HGNC (Hugo) | EOMES 3372 |
| Cards |
|---|
| Entrez_Gene (NCBI) | EOMES 8320 eomesodermin |
| Aliases | TBR2 |
| GeneCards (Weizmann) | EOMES |
| Ensembl hg19 (Hinxton) | ENSG00000163508 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000163508 [Gene_View] ENSG00000163508 [Sequence] chr3:27715949-27722715 [Contig_View] EOMES [Vega] |
| ICGC DataPortal | ENSG00000163508 |
| TCGA cBioPortal | EOMES |
| AceView (NCBI) | EOMES |
| Genatlas (Paris) | EOMES |
| WikiGenes | 8320 |
| SOURCE (Princeton) | EOMES |
| Genetics Home Reference (NIH) | EOMES |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | EOMES - chr3:27715949-27722715 - 3p24.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | EOMES - 3p24.1 [Description] (hg19-Feb_2009) |
| GoldenPath | EOMES - 3p24.1 [CytoView hg19] EOMES - 3p24.1 [CytoView hg38] |
| ImmunoBase | ENSG00000163508 |
| Mapping of homologs : NCBI | EOMES [Mapview hg19] EOMES [Mapview hg38] |
| OMIM | 604615 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB031038 AK297389 AK297461 AK299499 AK299695 |
| RefSeq transcript (Entrez) | NM_001278182 NM_001278183 NM_005442 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | EOMES |
| Cluster EST : Unigene | Hs.734211 [ NCBI ] |
| CGAP (NCI) | Hs.734211 |
| Alternative Splicing Gallery | ENSG00000163508 |
| Gene Expression | EOMES [ NCBI-GEO ] EOMES [ EBI - ARRAY_EXPRESS ]
EOMES [ SEEK ] EOMES [ MEM ] |
| Gene Expression Viewer (FireBrowse) | EOMES [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 8320 |
| GTEX Portal (Tissue expression) | EOMES |
| Human Protein Atlas | ENSG00000163508-EOMES [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O95936 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O95936 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O95936 |
| Splice isoforms : SwissVar | O95936 |
| PhosPhoSitePlus | O95936 |
| Domaine pattern : Prosite (Expaxy) | TBOX_1 (PS01283) TBOX_2 (PS01264) TBOX_3 (PS50252) |
| Domains : Interpro (EBI) | p53-like_TF_DNA-bd T-box_assoc T-box_sf TF_T-box TF_T-box_CS |
| Domain families : Pfam (Sanger) | T-box (PF00907) T-box_assoc (PF16176) |
| Domain families : Pfam (NCBI) | pfam00907 pfam16176 |
| Domain families : Smart (EMBL) | TBOX (SM00425) |
| Conserved Domain (NCBI) | EOMES |
| DMDM Disease mutations | 8320 |
| Blocks (Seattle) | EOMES |
| Superfamily | O95936 |
| Human Protein Atlas [tissue] | ENSG00000163508-EOMES [tissue] |
| Peptide Atlas | O95936 |
| HPRD | 07054 |
| IPI | IPI00296036 IPI00922382 IPI01009193 IPI00789239 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O95936 |
| IntAct (EBI) | O95936 |
| FunCoup | ENSG00000163508 |
| BioGRID | EOMES |
| STRING (EMBL) | EOMES |
| ZODIAC | EOMES |
| Ontologies - Pathways |
|---|
| QuickGO | O95936 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II activating transcription factor binding RNA polymerase II activating transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific endoderm formation mesoderm formation mesoderm formation cell fate specification endodermal cell fate specification endodermal cell fate specification trophectodermal cell differentiation adaptive immune response CD8-positive, alpha-beta T cell differentiation involved in immune response CD8-positive, alpha-beta T cell differentiation involved in immune response DNA binding chromatin binding nucleus brain development cardioblast differentiation stem cell population maintenance olfactory bulb development cerebral cortex regionalization cerebral cortex neuron differentiation interferon-gamma production skeletal muscle cell differentiation negative regulation of DNA-binding transcription factor activity sequence-specific DNA binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mesendoderm development cell differentiation involved in embryonic placenta development mesodermal to mesenchymal transition involved in gastrulation |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II activating transcription factor binding RNA polymerase II activating transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific endoderm formation mesoderm formation mesoderm formation cell fate specification endodermal cell fate specification endodermal cell fate specification trophectodermal cell differentiation adaptive immune response CD8-positive, alpha-beta T cell differentiation involved in immune response CD8-positive, alpha-beta T cell differentiation involved in immune response DNA binding chromatin binding nucleus brain development cardioblast differentiation stem cell population maintenance olfactory bulb development cerebral cortex regionalization cerebral cortex neuron differentiation interferon-gamma production skeletal muscle cell differentiation negative regulation of DNA-binding transcription factor activity sequence-specific DNA binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mesendoderm development cell differentiation involved in embryonic placenta development mesodermal to mesenchymal transition involved in gastrulation |
| NDEx Network | EOMES |
| Atlas of Cancer Signalling Network | EOMES |
| Wikipedia pathways | EOMES |
| Orthology - Evolution |
|---|
| OrthoDB | 8320 |
| GeneTree (enSembl) | ENSG00000163508 |
| Phylogenetic Trees/Animal Genes : TreeFam | EOMES |
| HOGENOM | O95936 |
| Homologs : HomoloGene | EOMES |
| Homology/Alignments : Family Browser (UCSC) | EOMES |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | EOMES/SLC4A7 [3p24.1/3p24.1] |
| Fusion : Quiver | EOMES |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | EOMES [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | EOMES |
| dbVar | EOMES |
| ClinVar | EOMES |
| 1000_Genomes | EOMES |
| Exome Variant Server | EOMES |
| ExAC (Exome Aggregation Consortium) | ENSG00000163508 |
| GNOMAD Browser | ENSG00000163508 |
| Varsome Browser | EOMES |
| Genetic variants : HAPMAP | 8320 |
| Genomic Variants (DGV) | EOMES [DGVbeta] |
| DECIPHER | EOMES [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | EOMES |
| Mutations |
|---|
| ICGC Data Portal | EOMES |
| TCGA Data Portal | EOMES |
| Broad Tumor Portal | EOMES |
| OASIS Portal | EOMES [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | EOMES [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | EOMES |
| Mutations and Diseases : HGMD | EOMES |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search EOMES |
| DgiDB (Drug Gene Interaction Database) | EOMES |
| DoCM (Curated mutations) | EOMES (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | EOMES (select a term) |
| intoGen | EOMES |
| Cancer3D | EOMES(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 604615 |
| Orphanet | 17930 |
| DisGeNET | EOMES |
| Medgen | EOMES |
| Genetic Testing Registry | EOMES
|
| NextProt | O95936 [Medical] |
| TSGene | 8320 |
| GENETests | EOMES |
| Target Validation | EOMES |
| Huge Navigator |
EOMES [HugePedia] |
| snp3D : Map Gene to Disease | 8320 |
| BioCentury BCIQ | EOMES |
| ClinGen | EOMES |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 8320 |
| Chemical/Pharm GKB Gene | PA27806 |
| Clinical trial | EOMES |
| Miscellaneous |
|---|
| canSAR (ICR) | EOMES (select the gene name) |
| DataMed Index | EOMES |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 52 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | EOMES |
| EVEX | EOMES |
| GoPubMed | EOMES |
| iHOP | EOMES |
