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EPS8L3 (EPS8 like 3)

Identity

Alias_namesEPS8-like 3
Alias_symbol (synonym)FLJ21522
MGC16817
Other aliasEPS8R3
HGNC (Hugo) EPS8L3
LocusID (NCBI) 79574
Atlas_Id 58049
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 109750080 and ends at 109764022 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EPS8L3   21297
Cards
Entrez_Gene (NCBI)EPS8L3  79574  EPS8 like 3
AliasesEPS8R3
GeneCards (Weizmann)EPS8L3
Ensembl hg19 (Hinxton)ENSG00000198758 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198758 [Gene_View]  ENSG00000198758 [Sequence]  chr1:109750080-109764022 [Contig_View]  EPS8L3 [Vega]
ICGC DataPortalENSG00000198758
TCGA cBioPortalEPS8L3
AceView (NCBI)EPS8L3
Genatlas (Paris)EPS8L3
WikiGenes79574
SOURCE (Princeton)EPS8L3
Genetics Home Reference (NIH)EPS8L3
Genomic and cartography
GoldenPath hg38 (UCSC)EPS8L3  -     chr1:109750080-109764022 -  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EPS8L3  -     1p13.3   [Description]    (hg19-Feb_2009)
GoldenPathEPS8L3 - 1p13.3 [CytoView hg19]  EPS8L3 - 1p13.3 [CytoView hg38]
ImmunoBaseENSG00000198758
Mapping of homologs : NCBIEPS8L3 [Mapview hg19]  EPS8L3 [Mapview hg38]
OMIM614989   
Gene and transcription
Genbank (Entrez)AK025175 AK225235 AK290261 AK292198 AK307932
RefSeq transcript (Entrez)NM_001319952 NM_024526 NM_133181 NM_139053
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EPS8L3
Cluster EST : UnigeneHs.485352 [ NCBI ]
CGAP (NCI)Hs.485352
Alternative Splicing GalleryENSG00000198758
Gene ExpressionEPS8L3 [ NCBI-GEO ]   EPS8L3 [ EBI - ARRAY_EXPRESS ]   EPS8L3 [ SEEK ]   EPS8L3 [ MEM ]
Gene Expression Viewer (FireBrowse)EPS8L3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79574
GTEX Portal (Tissue expression)EPS8L3
Human Protein AtlasENSG00000198758-EPS8L3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TE67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TE67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TE67
Splice isoforms : SwissVarQ8TE67
PhosPhoSitePlusQ8TE67
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)   
Domains : Interpro (EBI)EPS8_PTB    Eps8_SH3    PH-like_dom_sf    PTB    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)PTB (PF08416)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam08416    pfam00018   
Domain families : Smart (EMBL)SH3 (SM00326)  
Conserved Domain (NCBI)EPS8L3
DMDM Disease mutations79574
Blocks (Seattle)EPS8L3
PDB (RSDB)1WXT   
PDB Europe1WXT   
PDB (PDBSum)1WXT   
PDB (IMB)1WXT   
Structural Biology KnowledgeBase1WXT   
SCOP (Structural Classification of Proteins)1WXT   
CATH (Classification of proteins structures)1WXT   
SuperfamilyQ8TE67
Human Protein Atlas [tissue]ENSG00000198758-EPS8L3 [tissue]
Peptide AtlasQ8TE67
IPIIPI00181833   IPI00302864   IPI00256752   
Protein Interaction databases
DIP (DOE-UCLA)Q8TE67
IntAct (EBI)Q8TE67
FunCoupENSG00000198758
BioGRIDEPS8L3
STRING (EMBL)EPS8L3
ZODIACEPS8L3
Ontologies - Pathways
QuickGOQ8TE67
Ontology : AmiGOactin binding  protein binding  cytoplasm  plasma membrane  Rho protein signal transduction  Rac guanyl-nucleotide exchange factor activity  Rac guanyl-nucleotide exchange factor activity  ruffle membrane  regulation of Rho protein signal transduction  regulation of hair cycle  actin filament binding  positive regulation of ruffle assembly  
Ontology : EGO-EBIactin binding  protein binding  cytoplasm  plasma membrane  Rho protein signal transduction  Rac guanyl-nucleotide exchange factor activity  Rac guanyl-nucleotide exchange factor activity  ruffle membrane  regulation of Rho protein signal transduction  regulation of hair cycle  actin filament binding  positive regulation of ruffle assembly  
NDEx NetworkEPS8L3
Atlas of Cancer Signalling NetworkEPS8L3
Wikipedia pathwaysEPS8L3
Orthology - Evolution
OrthoDB79574
GeneTree (enSembl)ENSG00000198758
Phylogenetic Trees/Animal Genes : TreeFamEPS8L3
HOGENOMQ8TE67
Homologs : HomoloGeneEPS8L3
Homology/Alignments : Family Browser (UCSC)EPS8L3
Gene fusions - Rearrangements
Fusion : QuiverEPS8L3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEPS8L3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EPS8L3
dbVarEPS8L3
ClinVarEPS8L3
1000_GenomesEPS8L3 
Exome Variant ServerEPS8L3
ExAC (Exome Aggregation Consortium)ENSG00000198758
GNOMAD BrowserENSG00000198758
Varsome BrowserEPS8L3
Genetic variants : HAPMAP79574
Genomic Variants (DGV)EPS8L3 [DGVbeta]
DECIPHEREPS8L3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEPS8L3 
Mutations
ICGC Data PortalEPS8L3 
TCGA Data PortalEPS8L3 
Broad Tumor PortalEPS8L3
OASIS PortalEPS8L3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEPS8L3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DEPS8L3
Mutations and Diseases : HGMDEPS8L3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EPS8L3
DgiDB (Drug Gene Interaction Database)EPS8L3
DoCM (Curated mutations)EPS8L3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EPS8L3 (select a term)
intoGenEPS8L3
Cancer3DEPS8L3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614989   
Orphanet
DisGeNETEPS8L3
MedgenEPS8L3
Genetic Testing Registry EPS8L3
NextProtQ8TE67 [Medical]
TSGene79574
GENETestsEPS8L3
Target ValidationEPS8L3
Huge Navigator EPS8L3 [HugePedia]
snp3D : Map Gene to Disease79574
BioCentury BCIQEPS8L3
ClinGenEPS8L3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79574
Chemical/Pharm GKB GenePA134940846
Clinical trialEPS8L3
Miscellaneous
canSAR (ICR)EPS8L3 (select the gene name)
DataMed IndexEPS8L3
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEPS8L3
EVEXEPS8L3
GoPubMedEPS8L3
iHOPEPS8L3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:42:12 CET 2019

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