Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ERVFRD-1 (endogenous retrovirus group FRD member 1, envelope)

Identity

Alias (NCBI)ERVFRDE1
GLLL6191
HERV-FRD
HERV-W/FRD
UNQ6191
envFRD
HGNC (Hugo) ERVFRD-1
HGNC Alias symbHERV-W/FRD
HERV-FRD
envFRD
ERVFRDE1
syncytin-2
HGNC Previous nameendogenous retrovirus group FRD, member 1
 endogenous retrovirus group FRD member 1
LocusID (NCBI) 405754
Atlas_Id 56408
Location 6p24.2  [Link to chromosome band 6p24]
Location_base_pair Starts at 11102489 and ends at 11111725 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NOL7 (6p23) / ERVFRD-1 (6p24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p23;p24) NOL7/ERVFRD-1


External links

Nomenclature
HGNC (Hugo)ERVFRD-1   33823
Cards
Entrez_Gene (NCBI)ERVFRD-1  405754  endogenous retrovirus group FRD member 1, envelope
AliasesERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; 
UNQ6191; envFRD
GeneCards (Weizmann)ERVFRD-1
Ensembl hg19 (Hinxton)ENSG00000244476 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000244476 [Gene_View]  ENSG00000244476 [Sequence]  chr6:11102489-11111725 [Contig_View]  ERVFRD-1 [Vega]
ICGC DataPortalENSG00000244476
TCGA cBioPortalERVFRD-1
AceView (NCBI)ERVFRD-1
Genatlas (Paris)ERVFRD-1
WikiGenes405754
SOURCE (Princeton)ERVFRD-1
Genetics Home Reference (NIH)ERVFRD-1
Genomic and cartography
GoldenPath hg38 (UCSC)ERVFRD-1  -     chr6:11102489-11111725 -  6p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ERVFRD-1  -     6p24.2   [Description]    (hg19-Feb_2009)
GoldenPathERVFRD-1 - 6p24.2 [CytoView hg19]  ERVFRD-1 - 6p24.2 [CytoView hg38]
ImmunoBaseENSG00000244476
genome Data Viewer NCBIERVFRD-1 [Mapview hg19]  
OMIM610524   
Gene and transcription
Genbank (Entrez)AK075092 AK123938 AY358244 BC068585 DA863475
RefSeq transcript (Entrez)NM_207582
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ERVFRD-1
Alternative Splicing GalleryENSG00000244476
Gene ExpressionERVFRD-1 [ NCBI-GEO ]   ERVFRD-1 [ EBI - ARRAY_EXPRESS ]   ERVFRD-1 [ SEEK ]   ERVFRD-1 [ MEM ]
Gene Expression Viewer (FireBrowse)ERVFRD-1 [ Firebrowse - Broad ]
GenevisibleExpression of ERVFRD-1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)405754
GTEX Portal (Tissue expression)ERVFRD-1
Human Protein AtlasENSG00000244476-ERVFRD-1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP60508   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP60508  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP60508
Splice isoforms : SwissVarP60508
PhosPhoSitePlusP60508
Domains : Interpro (EBI)TLV/ENV_coat_polyprotein   
Domain families : Pfam (Sanger)TLV_coat (PF00429)   
Domain families : Pfam (NCBI)pfam00429   
Conserved Domain (NCBI)ERVFRD-1
DMDM Disease mutations405754
Blocks (Seattle)ERVFRD-1
PDB (RSDB)1Y4M    6RX3   
PDB Europe1Y4M    6RX3   
PDB (PDBSum)1Y4M    6RX3   
PDB (IMB)1Y4M    6RX3   
Structural Biology KnowledgeBase1Y4M    6RX3   
SCOP (Structural Classification of Proteins)1Y4M    6RX3   
CATH (Classification of proteins structures)1Y4M    6RX3   
SuperfamilyP60508
Human Protein Atlas [tissue]ENSG00000244476-ERVFRD-1 [tissue]
Peptide AtlasP60508
HPRD13648
IPIIPI00398064   
Protein Interaction databases
DIP (DOE-UCLA)P60508
IntAct (EBI)P60508
FunCoupENSG00000244476
BioGRIDERVFRD-1
STRING (EMBL)ERVFRD-1
ZODIACERVFRD-1
Ontologies - Pathways
QuickGOP60508
Ontology : AmiGOsyncytium formation by plasma membrane fusion  syncytium formation by plasma membrane fusion  plasma membrane  syncytium formation  myoblast fusion  integral component of membrane  
Ontology : EGO-EBIsyncytium formation by plasma membrane fusion  syncytium formation by plasma membrane fusion  plasma membrane  syncytium formation  myoblast fusion  integral component of membrane  
NDEx NetworkERVFRD-1
Atlas of Cancer Signalling NetworkERVFRD-1
Wikipedia pathwaysERVFRD-1
Orthology - Evolution
OrthoDB405754
GeneTree (enSembl)ENSG00000244476
Phylogenetic Trees/Animal Genes : TreeFamERVFRD-1
HOGENOMP60508
Homologs : HomoloGeneERVFRD-1
Homology/Alignments : Family Browser (UCSC)ERVFRD-1
Gene fusions - Rearrangements
Fusion : QuiverERVFRD-1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerERVFRD-1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ERVFRD-1
dbVarERVFRD-1
ClinVarERVFRD-1
1000_GenomesERVFRD-1 
Exome Variant ServerERVFRD-1
GNOMAD BrowserENSG00000244476
Varsome BrowserERVFRD-1
Genetic variants : HAPMAP405754
Genomic Variants (DGV)ERVFRD-1 [DGVbeta]
DECIPHERERVFRD-1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisERVFRD-1 
Mutations
ICGC Data PortalERVFRD-1 
TCGA Data PortalERVFRD-1 
Broad Tumor PortalERVFRD-1
OASIS PortalERVFRD-1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICERVFRD-1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DERVFRD-1
Mutations and Diseases : HGMDERVFRD-1
BioMutasearch ERVFRD-1
DgiDB (Drug Gene Interaction Database)ERVFRD-1
DoCM (Curated mutations)ERVFRD-1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ERVFRD-1 (select a term)
intoGenERVFRD-1
Cancer3DERVFRD-1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610524   
Orphanet
DisGeNETERVFRD-1
MedgenERVFRD-1
Genetic Testing Registry ERVFRD-1
NextProtP60508 [Medical]
TSGene405754
GENETestsERVFRD-1
Target ValidationERVFRD-1
Huge Navigator ERVFRD-1 [HugePedia]
snp3D : Map Gene to Disease405754
BioCentury BCIQERVFRD-1
ClinGenERVFRD-1
Clinical trials, drugs, therapy
Protein Interactions : CTD405754
Pharm GKB GenePA166180610
Clinical trialERVFRD-1
Miscellaneous
canSAR (ICR)ERVFRD-1 (select the gene name)
HarmonizomeERVFRD-1
DataMed IndexERVFRD-1
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineERVFRD-1
EVEXERVFRD-1
GoPubMedERVFRD-1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:12:26 CEST 2020

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.