| Nomenclature |
HGNC (Hugo) | ETV3 3492 |
| Cards |
Entrez_Gene (NCBI) | ETV3 2117 ETS variant transcription factor 3 |
Aliases | METS; PE-1; PE1 |
GeneCards (Weizmann) | ETV3 |
Ensembl hg19 (Hinxton) | ENSG00000117036 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000117036 [Gene_View]  ENSG00000117036 [Sequence] chr1:157133184-157138591 [Contig_View] ETV3 [Vega] |
ICGC DataPortal | ENSG00000117036 |
TCGA cBioPortal | ETV3 |
AceView (NCBI) | ETV3 |
Genatlas (Paris) | ETV3 |
WikiGenes | 2117 |
SOURCE (Princeton) | ETV3 |
Genetics Home Reference (NIH) | ETV3 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | ETV3 - chr1:157133184-157138591 - 1q23.1 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | ETV3 - 1q23.1 [Description] (hg19-Feb_2009) |
GoldenPath | ETV3 - 1q23.1 [CytoView hg19] ETV3 - 1q23.1 [CytoView hg38] |
ImmunoBase | ENSG00000117036 |
Mapping of homologs : NCBI | ETV3 [Mapview hg19] ETV3 [Mapview hg38] |
OMIM | 164873 |
| Gene and transcription |
Genbank (Entrez) | AF218540 AK304789 AK316274 BC022868 BU690105 |
RefSeq transcript (Entrez) | NM_001145312 NM_005240 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | ETV3 |
Cluster EST : Unigene | Hs.709764 [ NCBI ] |
CGAP (NCI) | Hs.709764 |
Alternative Splicing Gallery | ENSG00000117036 |
Gene Expression | ETV3 [ NCBI-GEO ] ETV3 [ EBI - ARRAY_EXPRESS ]
ETV3 [ SEEK ] ETV3 [ MEM ] |
Gene Expression Viewer (FireBrowse) | ETV3 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 2117 |
GTEX Portal (Tissue expression) | ETV3 |
Human Protein Atlas | ENSG00000117036-ETV3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | P41162 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | P41162 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | P41162 |
Splice isoforms : SwissVar | P41162 |
PhosPhoSitePlus | P41162 |
Domaine pattern : Prosite (Expaxy) | ETS_DOMAIN_1 (PS00345) ETS_DOMAIN_2 (PS00346) ETS_DOMAIN_3 (PS50061) |
Domains : Interpro (EBI) | Ets_dom ETV3 WH-like_DNA-bd_sf WH_DNA-bd_sf |
Domain families : Pfam (Sanger) | Ets (PF00178) |
Domain families : Pfam (NCBI) | pfam00178 |
Domain families : Smart (EMBL) | ETS (SM00413) |
Conserved Domain (NCBI) | ETV3 |
DMDM Disease mutations | 2117 |
Blocks (Seattle) | ETV3 |
Superfamily | P41162 |
Human Protein Atlas [tissue] | ENSG00000117036-ETV3 [tissue] |
Peptide Atlas | P41162 |
HPRD | 01282 |
IPI | IPI00032598 IPI00514913 |
| Protein Interaction databases |
DIP (DOE-UCLA) | P41162 |
IntAct (EBI) | P41162 |
FunCoup | ENSG00000117036 |
BioGRID | ETV3 |
STRING (EMBL) | ETV3 |
ZODIAC | ETV3 |
| Ontologies - Pathways |
QuickGO | P41162 |
Ontology : AmiGO | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific molecular_function nucleus regulation of transcription by RNA polymerase II biological_process negative regulation of cell proliferation DEAD/H-box RNA helicase binding cell differentiation RNA polymerase II transcription repressor complex cellular response to granulocyte macrophage colony-stimulating factor stimulus |
Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific molecular_function nucleus regulation of transcription by RNA polymerase II biological_process negative regulation of cell proliferation DEAD/H-box RNA helicase binding cell differentiation RNA polymerase II transcription repressor complex cellular response to granulocyte macrophage colony-stimulating factor stimulus |
NDEx Network | ETV3 |
Atlas of Cancer Signalling Network | ETV3 |
Wikipedia pathways | ETV3 |
| Orthology - Evolution |
OrthoDB | 2117 |
GeneTree (enSembl) | ENSG00000117036 |
Phylogenetic Trees/Animal Genes : TreeFam | ETV3 |
HOGENOM | P41162 |
Homologs : HomoloGene | ETV3 |
Homology/Alignments : Family Browser (UCSC) | ETV3 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | ARHGEF11/ETV3 [1q23.1/1q23.1]  [t(1;1)(q23;q23)] |
Fusion : Mitelman | ETV3/MNDA [1q23.1/1q23.1]  [t(1;1)(q23;q23)] |
Fusion : Mitelman | IKZF3/ETV3 [17q12/1q23.1]  [t(1;17)(q23;q12)] |
Fusion : Mitelman | IQGAP3/ETV3 [1q22/1q23.1]  [t(1;1)(q23;q23)] |
Fusion Portal | ARHGEF11 1q23.1 ETV3 1q23.1 BRCA |
Fusion Portal | ETV3 1q23.1 MNDA 1q23.1 PRAD |
Fusion Portal | IQGAP3 1q22 ETV3 1q23.1 BRCA |
Fusion : Quiver | ETV3 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | ETV3 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | ETV3 |
dbVar | ETV3 |
ClinVar | ETV3 |
1000_Genomes | ETV3 |
Exome Variant Server | ETV3 |
ExAC (Exome Aggregation Consortium) | ENSG00000117036 |
GNOMAD Browser | ENSG00000117036 |
Varsome Browser | ETV3 |
Genetic variants : HAPMAP | 2117 |
Genomic Variants (DGV) | ETV3 [DGVbeta] |
DECIPHER | ETV3 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | ETV3 |
| Mutations |
ICGC Data Portal | ETV3 |
TCGA Data Portal | ETV3 |
Broad Tumor Portal | ETV3 |
OASIS Portal | ETV3 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | ETV3 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | ETV3 |
Mutations and Diseases : HGMD | ETV3 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search ETV3 |
DgiDB (Drug Gene Interaction Database) | ETV3 |
DoCM (Curated mutations) | ETV3 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | ETV3 (select a term) |
intoGen | ETV3 |
Cancer3D | ETV3(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 164873 |
Orphanet | |
DisGeNET | ETV3 |
Medgen | ETV3 |
Genetic Testing Registry | ETV3
|
NextProt | P41162 [Medical] |
TSGene | 2117 |
GENETests | ETV3 |
Target Validation | ETV3 |
Huge Navigator |
ETV3 [HugePedia] |
snp3D : Map Gene to Disease | 2117 |
BioCentury BCIQ | ETV3 |
ClinGen | ETV3 |
| Clinical trials, drugs, therapy |
---|
Chemical/Protein Interactions : CTD | 2117 |
Chemical/Pharm GKB Gene | PA27906 |
Clinical trial | ETV3 |
| Miscellaneous |
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canSAR (ICR) | ETV3 (select the gene name) |
DataMed Index | ETV3 |
| Probes |
---|
| Litterature |
---|
PubMed | 27 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | ETV3 |
EVEX | ETV3 |
GoPubMed | ETV3 |
iHOP | ETV3 |