| Nomenclature |
|---|
| HGNC (Hugo) | ETV3 3492 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ETV3 2117 ETS variant transcription factor 3 |
| Aliases | METS; PE-1; PE1 |
| GeneCards (Weizmann) | ETV3 |
| Ensembl hg19 (Hinxton) | ENSG00000117036 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000117036 [Gene_View] ENSG00000117036 [Sequence] chr1:157133184-157138591 [Contig_View] ETV3 [Vega] |
| ICGC DataPortal | ENSG00000117036 |
| TCGA cBioPortal | ETV3 |
| AceView (NCBI) | ETV3 |
| Genatlas (Paris) | ETV3 |
| WikiGenes | 2117 |
| SOURCE (Princeton) | ETV3 |
| Genetics Home Reference (NIH) | ETV3 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ETV3 - chr1:157133184-157138591 - 1q23.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ETV3 - 1q23.1 [Description] (hg19-Feb_2009) |
| GoldenPath | ETV3 - 1q23.1 [CytoView hg19] ETV3 - 1q23.1 [CytoView hg38] |
| ImmunoBase | ENSG00000117036 |
| Mapping of homologs : NCBI | ETV3 [Mapview hg19] ETV3 [Mapview hg38] |
| OMIM | 164873 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF218540 AK304789 AK316274 BC022868 BU690105 |
| RefSeq transcript (Entrez) | NM_001145312 NM_005240 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ETV3 |
| Cluster EST : Unigene | Hs.709764 [ NCBI ] |
| CGAP (NCI) | Hs.709764 |
| Alternative Splicing Gallery | ENSG00000117036 |
| Gene Expression | ETV3 [ NCBI-GEO ] ETV3 [ EBI - ARRAY_EXPRESS ]
ETV3 [ SEEK ] ETV3 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ETV3 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 2117 |
| GTEX Portal (Tissue expression) | ETV3 |
| Human Protein Atlas | ENSG00000117036-ETV3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P41162 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P41162 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P41162 |
| Splice isoforms : SwissVar | P41162 |
| PhosPhoSitePlus | P41162 |
| Domaine pattern : Prosite (Expaxy) | ETS_DOMAIN_1 (PS00345) ETS_DOMAIN_2 (PS00346) ETS_DOMAIN_3 (PS50061) |
| Domains : Interpro (EBI) | Ets_dom ETV3 WH-like_DNA-bd_sf WH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | Ets (PF00178) |
| Domain families : Pfam (NCBI) | pfam00178 |
| Domain families : Smart (EMBL) | ETS (SM00413) |
| Conserved Domain (NCBI) | ETV3 |
| DMDM Disease mutations | 2117 |
| Blocks (Seattle) | ETV3 |
| Superfamily | P41162 |
| Human Protein Atlas [tissue] | ENSG00000117036-ETV3 [tissue] |
| Peptide Atlas | P41162 |
| HPRD | 01282 |
| IPI | IPI00032598 IPI00514913 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P41162 |
| IntAct (EBI) | P41162 |
| FunCoup | ENSG00000117036 |
| BioGRID | ETV3 |
| STRING (EMBL) | ETV3 |
| ZODIAC | ETV3 |
| Ontologies - Pathways |
|---|
| QuickGO | P41162 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific molecular_function nucleus regulation of transcription by RNA polymerase II biological_process negative regulation of cell proliferation DEAD/H-box RNA helicase binding cell differentiation RNA polymerase II transcription repressor complex cellular response to granulocyte macrophage colony-stimulating factor stimulus |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific molecular_function nucleus regulation of transcription by RNA polymerase II biological_process negative regulation of cell proliferation DEAD/H-box RNA helicase binding cell differentiation RNA polymerase II transcription repressor complex cellular response to granulocyte macrophage colony-stimulating factor stimulus |
| NDEx Network | ETV3 |
| Atlas of Cancer Signalling Network | ETV3 |
| Wikipedia pathways | ETV3 |
| Orthology - Evolution |
|---|
| OrthoDB | 2117 |
| GeneTree (enSembl) | ENSG00000117036 |
| Phylogenetic Trees/Animal Genes : TreeFam | ETV3 |
| HOGENOM | P41162 |
| Homologs : HomoloGene | ETV3 |
| Homology/Alignments : Family Browser (UCSC) | ETV3 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | ARHGEF11/ETV3 [1q23.1/1q23.1] [t(1;1)(q23;q23)] |
| Fusion : Mitelman | ETV3/MNDA [1q23.1/1q23.1] [t(1;1)(q23;q23)] |
| Fusion : Mitelman | IKZF3/ETV3 [17q12/1q23.1] [t(1;17)(q23;q12)] |
| Fusion : Mitelman | IQGAP3/ETV3 [1q22/1q23.1] [t(1;1)(q23;q23)] |
| Fusion Portal | ARHGEF11 1q23.1 ETV3 1q23.1 BRCA |
| Fusion Portal | ETV3 1q23.1 MNDA 1q23.1 PRAD |
| Fusion Portal | IQGAP3 1q22 ETV3 1q23.1 BRCA |
| Fusion : Quiver | ETV3 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ETV3 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ETV3 |
| dbVar | ETV3 |
| ClinVar | ETV3 |
| 1000_Genomes | ETV3 |
| Exome Variant Server | ETV3 |
| ExAC (Exome Aggregation Consortium) | ENSG00000117036 |
| GNOMAD Browser | ENSG00000117036 |
| Varsome Browser | ETV3 |
| Genetic variants : HAPMAP | 2117 |
| Genomic Variants (DGV) | ETV3 [DGVbeta] |
| DECIPHER | ETV3 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ETV3 |
| Mutations |
|---|
| ICGC Data Portal | ETV3 |
| TCGA Data Portal | ETV3 |
| Broad Tumor Portal | ETV3 |
| OASIS Portal | ETV3 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ETV3 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | ETV3 |
| Mutations and Diseases : HGMD | ETV3 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search ETV3 |
| DgiDB (Drug Gene Interaction Database) | ETV3 |
| DoCM (Curated mutations) | ETV3 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ETV3 (select a term) |
| intoGen | ETV3 |
| Cancer3D | ETV3(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 164873 |
| Orphanet | |
| DisGeNET | ETV3 |
| Medgen | ETV3 |
| Genetic Testing Registry | ETV3
|
| NextProt | P41162 [Medical] |
| TSGene | 2117 |
| GENETests | ETV3 |
| Target Validation | ETV3 |
| Huge Navigator |
ETV3 [HugePedia] |
| snp3D : Map Gene to Disease | 2117 |
| BioCentury BCIQ | ETV3 |
| ClinGen | ETV3 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 2117 |
| Chemical/Pharm GKB Gene | PA27906 |
| Clinical trial | ETV3 |
| Miscellaneous |
|---|
| canSAR (ICR) | ETV3 (select the gene name) |
| DataMed Index | ETV3 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 27 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ETV3 |
| EVEX | ETV3 |
| GoPubMed | ETV3 |
| iHOP | ETV3 |
