EVA1A (eva-1 homolog A, regulator of programmed cell death)

2013-05-01  

Identity

HGNC
LOCATION
2p12
LOCUSID
ALIAS
FAM176A,TMEM166
FUSION GENES

Other Information

Locus ID:

NCBI: 84141
HGNC: 25816
Ensembl: ENSG00000115363

Variants:

dbSNP: 84141
ClinVar: 84141
TCGA: ENSG00000115363
COSMIC: EVA1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115363ENST00000233712Q9H8M9
ENSG00000115363ENST00000393913Q9H8M9
ENSG00000115363ENST00000410010B8ZZF5
ENSG00000115363ENST00000410071Q9H8M9
ENSG00000115363ENST00000410113Q9H8M9
ENSG00000115363ENST00000432649C9J5M4
ENSG00000115363ENST00000452003C9JX09

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
174924042007TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis.23
274909282016TMEM166/EVA1A interacts with ATG16L1 and induces autophagosome formation and cell death.14
242571182014Adenovirus vector-mediated FAM176A overexpression induces cell death in human H1299 non-small cell lung cancer cells.11
297493742018MicroRNA-125b reverses oxaliplatin resistance in hepatocellular carcinoma by negatively regulating EVA1A mediated autophagy.8
224953692013Expression of TMEM166 protein in human normal and tumor tissues.7
230984602012Transmembrane protein 166 expression in esophageal squamous cell carcinoma in Xinjiang, China.5
281858342017EVA1A inhibits GBM cell proliferation by inducing autophagy and apoptosis.5

Citation

Dessen P

EVA1A (eva-1 homolog A, regulator of programmed cell death)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53273/eva1a