EVI5 (ecotropic viral integration site 5)

2003-02-01  

Identity

HGNC
EVI5
LOCATION
1p22.1
LOCUSID
7813
ALIAS
EVI-5,NB4S
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7813
MIM: 602942
HGNC: 3501
Ensembl: ENSG00000067208

Variants:

dbSNP: 7813
ClinVar: 7813
TCGA: ENSG00000067208
COSMIC: EVI5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000067208ENST00000370331O60447
ENSG00000067208ENST00000491940A0A1B0GUF4
ENSG00000067208ENST00000540033O60447

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
200087902010Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis.37
172298372007Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene.36
198651022010Multiple sclerosis susceptibility alleles in African Americans.35
255375162015MicroRNA-135b, a HSF1 target, promotes tumor invasion and metastasis by regulating RECK and EVI5 in hepatocellular carcinoma.27
184013522008EVI5 is a risk gene for multiple sclerosis.26
184013522008EVI5 is a risk gene for multiple sclerosis.26
198345032009Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.26
195062192009Risk alleles for multiple sclerosis in multiplex families.18
236693552013The Evi5 family in cellular physiology and pathology.11
200874032010Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis.10

Citation

Dessen P

EVI5 (ecotropic viral integration site 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40511/evi5