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EYA3 (EYA transcriptional coactivator and phosphatase 3)

Identity

Other names-
HGNC (Hugo) EYA3
LocusID (NCBI) 2140
Location 1p35.3
Location_base_pair Starts at 28303784 and ends at 28415148 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EYA3   3521
Cards
Entrez_Gene (NCBI)EYA3  2140  EYA transcriptional coactivator and phosphatase 3
GeneCards (Weizmann)EYA3
Ensembl (Hinxton)ENSG00000158161 [Gene_View]  chr1:28303784-28415148 [Contig_View]  EYA3 [Vega]
ICGC DataPortalENSG00000158161
cBioPortalEYA3
AceView (NCBI)EYA3
Genatlas (Paris)EYA3
WikiGenes2140
SOURCE (Princeton)NM_001282560 NM_001282561 NM_001282562 NM_001990 NM_172098
Genomic and cartography
GoldenPath (UCSC)EYA3  -  1p35.3   chr1:28303784-28415148 -  1p35.3   [Description]    (hg19-Feb_2009)
EnsemblEYA3 - 1p35.3 [CytoView]
Mapping of homologs : NCBIEYA3 [Mapview]
OMIM601655   
Gene and transcription
Genbank (Entrez)AJ007991 AK289805 AK295745 AK298129 AK303664
RefSeq transcript (Entrez)NM_001282560 NM_001282561 NM_001282562 NM_001990 NM_172098
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_032977 NW_001838576 NW_004929289
Consensus coding sequences : CCDS (NCBI)EYA3
Cluster EST : UnigeneHs.185774 [ NCBI ]
CGAP (NCI)Hs.185774
Alternative Splicing : Fast-db (Paris)GSHG0001904
Alternative Splicing GalleryENSG00000158161
Gene ExpressionEYA3 [ NCBI-GEO ]     EYA3 [ SEEK ]   EYA3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99504 (Uniprot)
NextProtQ99504  [Medical]
With graphics : InterProQ99504
Splice isoforms : SwissVarQ99504 (Swissvar)
Domains : Interpro (EBI)EYA3 [organisation]   EYA_dom [organisation]   EYA_fam [organisation]  
Related proteins : CluSTrQ99504
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations2140
Blocks (Seattle)Q99504
Human Protein AtlasENSG00000158161 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ99504
HPRD09042
IPIIPI00015990   IPI00216103   IPI01013722   IPI01015164   IPI00238521   
Protein Interaction databases
DIP (DOE-UCLA)Q99504
IntAct (EBI)Q99504
FunCoupENSG00000158161
BioGRIDEYA3
InParanoidQ99504
Interologous Interaction database Q99504
IntegromeDBEYA3
STRING (EMBL)EYA3
Ontologies - Pathways
Ontology : AmiGOchromatin binding  protein tyrosine phosphatase activity  protein binding  nucleus  transcription factor complex  cytoplasm  double-strand break repair  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organismal development  visual perception  protein tyrosine/serine/threonine phosphatase activity  anatomical structure morphogenesis  response to ionizing radiation  histone dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  positive regulation of DNA repair  metal ion binding  
Ontology : EGO-EBIchromatin binding  protein tyrosine phosphatase activity  protein binding  nucleus  transcription factor complex  cytoplasm  double-strand break repair  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organismal development  visual perception  protein tyrosine/serine/threonine phosphatase activity  anatomical structure morphogenesis  response to ionizing radiation  histone dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  positive regulation of DNA repair  metal ion binding  
Protein Interaction DatabaseEYA3
Wikipedia pathwaysEYA3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)EYA3
snp3D : Map Gene to Disease2140
SNP (GeneSNP Utah)EYA3
SNP : HGBaseEYA3
Genetic variants : HAPMAPEYA3
Exome VariantEYA3
1000_GenomesEYA3 
ICGC programENSG00000158161 
Somatic Mutations in Cancer : COSMICEYA3 
CONAN: Copy Number AnalysisEYA3 
Mutations and Diseases : HGMDEYA3
Mutations and Diseases : intOGenEYA3
Genomic VariantsEYA3  EYA3 [DGVbeta]
dbVarEYA3
ClinVarEYA3
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM601655   
MedgenEYA3
GENETestsEYA3
Disease Genetic AssociationEYA3
Huge Navigator EYA3 [HugePedia]  EYA3 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneEYA3
Homology/Alignments : Family Browser (UCSC)EYA3
Phylogenetic Trees/Animal Genes : TreeFamEYA3
Chemical/Protein Interactions : CTD2140
Chemical/Pharm GKB GenePA27933
Clinical trialEYA3
Cancer Resource (Charite)ENSG00000158161
Other databases
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
CoreMineEYA3
iHOPEYA3
OncoSearchEYA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:50:21 CEST 2014

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