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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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EYA3 (EYA transcriptional coactivator and phosphatase 3)

Identity

Other names-
HGNC (Hugo) EYA3
LocusID (NCBI) 2140
Location 1p35.3
Location_base_pair Starts at 28303784 and ends at 28415148 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EYA3   3521
Cards
Entrez_Gene (NCBI)EYA3  2140  EYA transcriptional coactivator and phosphatase 3
GeneCards (Weizmann)EYA3
Ensembl hg19 (Hinxton)ENSG00000158161 [Gene_View]  chr1:28303784-28415148 [Contig_View]  EYA3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000158161 [Gene_View]  chr1:28303784-28415148 [Contig_View]  EYA3 [Vega]
ICGC DataPortalENSG00000158161
cBioPortalEYA3
AceView (NCBI)EYA3
Genatlas (Paris)EYA3
WikiGenes2140
SOURCE (Princeton)EYA3
Genomic and cartography
GoldenPath hg19 (UCSC)EYA3  -     chr1:28303784-28415148 -  1p35.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EYA3  -     1p35.3   [Description]    (hg38-Dec_2013)
EnsemblEYA3 - 1p35.3 [CytoView hg19]  EYA3 - 1p35.3 [CytoView hg38]
Mapping of homologs : NCBIEYA3 [Mapview hg19]  EYA3 [Mapview hg38]
OMIM601655   
Gene and transcription
Genbank (Entrez)AJ007991 AK289805 AK295745 AK298129 AK303664
RefSeq transcript (Entrez)NM_001282560 NM_001282561 NM_001282562 NM_001990 NM_172098
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)EYA3
Cluster EST : UnigeneHs.185774 [ NCBI ]
CGAP (NCI)Hs.185774
Alternative Splicing : Fast-db (Paris)GSHG0001904
Alternative Splicing GalleryENSG00000158161
Gene ExpressionEYA3 [ NCBI-GEO ]     EYA3 [ SEEK ]   EYA3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99504 (Uniprot)
NextProtQ99504  [Medical]
With graphics : InterProQ99504
Splice isoforms : SwissVarQ99504 (Swissvar)
Domains : Interpro (EBI)EYA3    EYA_dom    EYA_fam   
Related proteins : CluSTrQ99504
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations2140
Blocks (Seattle)Q99504
Human Protein AtlasENSG00000158161
Peptide AtlasQ99504
HPRD09042
IPIIPI00015990   IPI00216103   IPI01013722   IPI01015164   IPI00238521   
Protein Interaction databases
DIP (DOE-UCLA)Q99504
IntAct (EBI)Q99504
FunCoupENSG00000158161
BioGRIDEYA3
IntegromeDBEYA3
STRING (EMBL)EYA3
Ontologies - Pathways
QuickGOQ99504
Ontology : AmiGOchromatin binding  protein tyrosine phosphatase activity  protein binding  nucleus  nucleoplasm  transcription factor complex  cytoplasm  centrosome  double-strand break repair  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organismal development  visual perception  protein tyrosine/serine/threonine phosphatase activity  anatomical structure morphogenesis  response to ionizing radiation  histone dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  positive regulation of DNA repair  metal ion binding  
Ontology : EGO-EBIchromatin binding  protein tyrosine phosphatase activity  protein binding  nucleus  nucleoplasm  transcription factor complex  cytoplasm  centrosome  double-strand break repair  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organismal development  visual perception  protein tyrosine/serine/threonine phosphatase activity  anatomical structure morphogenesis  response to ionizing radiation  histone dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  positive regulation of DNA repair  metal ion binding  
Protein Interaction DatabaseEYA3
DoCM (Curated mutations)EYA3
Wikipedia pathwaysEYA3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerEYA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EYA3
dbVarEYA3
ClinVarEYA3
1000_GenomesEYA3 
Exome Variant ServerEYA3
SNP (GeneSNP Utah)EYA3
SNP : HGBaseEYA3
Genetic variants : HAPMAPEYA3
Genomic Variants (DGV)EYA3 [DGVbeta]
Mutations
ICGC Data PortalENSG00000158161 
Somatic Mutations in Cancer : COSMICEYA3 
CONAN: Copy Number AnalysisEYA3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:28303784-28415148
Mutations and Diseases : HGMDEYA3
OMIM601655   
MedgenEYA3
NextProtQ99504 [Medical]
GENETestsEYA3
Disease Genetic AssociationEYA3
Huge Navigator EYA3 [HugePedia]  EYA3 [HugeCancerGEM]
snp3D : Map Gene to Disease2140
DGIdb (Drug Gene Interaction db)EYA3
General knowledge
Homologs : HomoloGeneEYA3
Homology/Alignments : Family Browser (UCSC)EYA3
Phylogenetic Trees/Animal Genes : TreeFamEYA3
Chemical/Protein Interactions : CTD2140
Chemical/Pharm GKB GenePA27933
Clinical trialEYA3
Cancer Resource (Charite)ENSG00000158161
Other databases
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
CoreMineEYA3
GoPubMedEYA3
iHOPEYA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:19:38 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.