Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2160
MIM: 264900
HGNC: 3529
Ensembl: ENSG00000088926
Variants:
dbSNP: 2160
ClinVar: 2160
TCGA: ENSG00000088926
COSMIC: F11
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA452637 | hormonal contraceptives for systemic use | Chemical | ClinicalAnnotation | associated | PD | 28750087 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38194679 | 2024 | Factor XI deficiency: phenotypic age-related considerations and clinical approach towards bleeding risk assessment. | 2 |
| 38194679 | 2024 | Factor XI deficiency: phenotypic age-related considerations and clinical approach towards bleeding risk assessment. | 2 |
| 36724509 | 2023 | Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation. | 0 |
| 36940803 | 2023 | Impact of genetic structural variants in factor XI deficiency: identification, accurate characterization, and inferred mechanism by long-read sequencing. | 1 |
| 37141257 | 2023 | The unknown functions of a known protein: the case of coagulation factor XI. | 0 |
| 37252892 | 2023 | A focus on dominant negative variants in a series of 170 heterozygous FXI-deficient patients. | 0 |
| 37460982 | 2023 | Elevated plasma factor XI predicts cardiovascular events in patients with type 2 diabetes: a long-term observational study. | 3 |
| 37906134 | 2023 | [Analysis of a Chinese pedigree affected with Hereditary coagulation factor Ⅺ deficiency due to variant of F11 gene]. | 0 |
| 36724509 | 2023 | Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation. | 0 |
| 36940803 | 2023 | Impact of genetic structural variants in factor XI deficiency: identification, accurate characterization, and inferred mechanism by long-read sequencing. | 1 |
| 37141257 | 2023 | The unknown functions of a known protein: the case of coagulation factor XI. | 0 |
| 37252892 | 2023 | A focus on dominant negative variants in a series of 170 heterozygous FXI-deficient patients. | 0 |
| 37460982 | 2023 | Elevated plasma factor XI predicts cardiovascular events in patients with type 2 diabetes: a long-term observational study. | 3 |
| 37906134 | 2023 | [Analysis of a Chinese pedigree affected with Hereditary coagulation factor Ⅺ deficiency due to variant of F11 gene]. | 0 |
| 35377529 | 2022 | Sulfonated non-saccharide molecules and human factor XIa: Enzyme inhibition and computational studies. | 5 |
Citation
Dessen P
F11 (coagulation factor XI)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40519/f11
