FABP6 (fatty acid binding protein 6)

2007-12-01 Affiliation

Identity

HGNC

FABP6

LOCATION

5q33.3

LOCUSID

2172

ALIAS

I-15P,I-BABP,I-BALB,I-BAP,ILBP,ILBP3,ILLBP

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 2172
MIM: 600422
HGNC: 3561
Ensembl: ENSG00000170231

Variants:

dbSNP: 2172
ClinVar: 2172
TCGA: ENSG00000170231
COSMIC: FABP6

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000170231	ENST00000393980	P51161
ENSG00000170231	ENST00000402432	P51161
ENSG00000170231	ENST00000523955	H0YB64

Expression (GTEx)

100

150

200

250

300

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
PPAR signaling pathway	KEGG	ko03320
PPAR signaling pathway	KEGG	hsa03320
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Lipid digestion, mobilization, and transport	REACTOME	R-HSA-73923
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis	REACTOME	R-HSA-163560
Bile acid and bile salt metabolism	REACTOME	R-HSA-194068
Recycling of bile acids and salts	REACTOME	R-HSA-159418

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
16237211	2006	Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers.	16
12486725	2003	Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures.	13
16951225	2006	Fatty acid binding protein 6 is overexpressed in colorectal cancer.	13
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
17266179	2007	Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort - role of fat assimilation.	8
15936983	2005	The gene encoding the human ileal bile acid-binding protein (I-BABP) is regulated by peroxisome proliferator-activated receptors.	5
22329738	2012	Internal motions and exchange processes in human ileal bile acid binding protein as studied by backbone (15)N nuclear magnetic resonance spectroscopy.	5
14654244	2003	Human ileal bile acid-binding protein promoter and the effects of CDX2.	4
22223860	2012	Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα.	4

Citation

Dessen P

FABP6 (fatty acid binding protein 6)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49863/fabp6