Identity
HGNC
LOCATION
11q12.2
LOCUSID
ALIAS
D6D,DES6,FADSD6,LLCDL2,SLL0262,TU13
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9415
MIM: 606149
HGNC: 3575
Ensembl: ENSG00000134824
Variants:
dbSNP: 9415
ClinVar: 9415
TCGA: ENSG00000134824
COSMIC: FADS2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443450 | Asthma | Disease | Literature, MultilinkAnnotation | associated | 24934276 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38316767 | 2024 | Brain tissue- and cell type-specific eQTL Mendelian randomization reveals efficacy of FADS1 and FADS2 on cognitive function. | 0 |
| 38566550 | 2024 | Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: A genetic association study. | 0 |
| 38849435 | 2024 | FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response. | 0 |
| 38316767 | 2024 | Brain tissue- and cell type-specific eQTL Mendelian randomization reveals efficacy of FADS1 and FADS2 on cognitive function. | 0 |
| 38566550 | 2024 | Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: A genetic association study. | 0 |
| 38849435 | 2024 | FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response. | 0 |
| 36652541 | 2023 | Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies. | 1 |
| 36788508 | 2023 | The integrative panel of fatty acid desaturase-2 (FADS2) rs174583 gene polymorphism and dietary indices (DQI-I and HEI) affects cardiovascular risk factors among obese individuals. | 0 |
| 36788618 | 2023 | The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomes. | 0 |
| 36864135 | 2023 | Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus. | 10 |
| 37506860 | 2023 | Hsa_circ_0000073 promotes lipid synthesis of osteosarcoma through hsa-miR-1184/ FADS2 pathway. | 3 |
| 36652541 | 2023 | Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies. | 1 |
| 36788508 | 2023 | The integrative panel of fatty acid desaturase-2 (FADS2) rs174583 gene polymorphism and dietary indices (DQI-I and HEI) affects cardiovascular risk factors among obese individuals. | 0 |
| 36788618 | 2023 | The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomes. | 0 |
| 36864135 | 2023 | Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus. | 10 |
Citation
Dessen P
FADS2 (fatty acid desaturase 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46480/fads2
