FAIM2 (Fas apoptotic inhibitory molecule 2)

2006-10-01  

Identity

HGNC
FAIM2
LOCATION
12q13.12
LOCUSID
23017
ALIAS
LFG,LFG2,NGP35,NMP35,TMBIM2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23017
MIM: 604306
HGNC: 17067
Ensembl: ENSG00000135472

Variants:

dbSNP: 23017
ClinVar: 23017
TCGA: ENSG00000135472
COSMIC: FAIM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135472ENST00000320634Q9BWQ8
ENSG00000135472ENST00000547871F8VV65
ENSG00000135472ENST00000550195F8VZI9
ENSG00000135472ENST00000550635A0A0A0MTP9
ENSG00000135472ENST00000550890Q9BWQ8
ENSG00000135472ENST00000552669F8W1L3
ENSG00000135472ENST00000552863H0YIR3

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
198121712010Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.74
202153972010Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.44
208161952010Analyses of shared genetic factors between asthma and obesity in children.43
219353972011Genome-wide population-based association study of extremely overweight young adults--the GOYA study.43
291314402018miR-193b availability is antagonized by LncRNA-SNHG7 for FAIM2-induced tumour progression in non-small cell lung cancer.38
198513402009Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.37
198513402009Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.37
208439812010Associations of six single nucleotide polymorphisms in obesity-related genes with BMI and risk of obesity in Chinese children.36
276669642016lncRNA-SNHG7 promotes the proliferation, migration and invasion and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression.30
257649782015The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.23

Citation

Dessen P

FAIM2 (Fas apoptotic inhibitory molecule 2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43252/faim2