FAM120A (family with sequence similarity 120A)

2009-05-01  

Identity

HGNC
LOCATION
9q22.31
LOCUSID
ALIAS
C9orf10,HBVPTPAP,OSSA
FUSION GENES

Other Information

Locus ID:

NCBI: 23196
MIM: 612265
HGNC: 13247
Ensembl: ENSG00000048828

Variants:

dbSNP: 23196
ClinVar: 23196
TCGA: ENSG00000048828
COSMIC: FAM120A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000048828ENST00000277165Q9NZB2
ENSG00000048828ENST00000375389Q9NZB2
ENSG00000048828ENST00000427765A0A0C4DG79
ENSG00000048828ENST00000446420A0A0C4DH52
ENSG00000048828ENST00000652239A0A494C0Y9

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
259537832015A genome-wide association study of body mass index across early life and childhood.39
258963272015IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.24
277568052016Widespread structural brain involvement in ALS is not limited to the C9orf72 repeat expansion.13
190152442009A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis.12

Citation

Dessen P

FAM120A (family with sequence similarity 120A)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50866/fam120a