FAM83A (family with sequence similarity 83 member A)

2007-02-01  

Identity

HGNC
FAM83A
LOCATION
8q24.13
LOCUSID
84985
ALIAS
BJ-TSA-9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84985
HGNC: 28210
Ensembl: ENSG00000147689

Variants:

dbSNP: 84985
ClinVar: 84985
TCGA: ENSG00000147689
COSMIC: FAM83A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147689ENST00000276699Q86UY5
ENSG00000147689ENST00000518448Q86UY5
ENSG00000147689ENST00000522648Q86UY5
ENSG00000147689ENST00000536633Q86UY5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
228863032012FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice.49
163545902005BJ-TSA-9, a novel human tumor-specific gene, has potential as a biomarker of lung cancer.29
185140662008Detection of circulating cancer cells in lung cancer patients with a panel of marker genes.27
284639692017HER2-positive breast cancer cells expressing elevated FAM83A are sensitive to FAM83A loss.8
311758042019Overexpression of Family with Sequence Similarity 83, Member A (FAM83A) Predicts Poor Clinical Outcomes in Lung Adenocarcinoma.1
315942122019Elevated FAM83A expression predicts poorer clincal outcome in lung adenocarcinoma.0
322822282020FAM83A Is a Prognosis Signature and Potential Oncogene of Lung Adenocarcinoma.0

Citation

Dessen P

FAM83A (family with sequence similarity 83 member A)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43791/fam83a