Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
FAS,OA-519,SDR27X1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2194
MIM: 600212
HGNC: 3594
Ensembl: ENSG00000169710
Variants:
dbSNP: 2194
ClinVar: 2194
TCGA: ENSG00000169710
COSMIC: FASN
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38112617 | 2024 | FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-genomic Features of Prostate Cancer. | 0 |
| 38117249 | 2024 | The Regulation of Fatty Acid Synthase by Exosomal miR-143-5p and miR-342-5p in Idiopathic Pulmonary Fibrosis. | 1 |
| 38143182 | 2024 | FAS/SREBP-1c contributes to colorectal carcinogenesis through calcium signaling pathway and cAMP signaling pathway. | 0 |
| 38218866 | 2024 | Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer. | 2 |
| 38228715 | 2024 | GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4. | 0 |
| 38291470 | 2024 | PITPNC1 Suppress CD8(+) T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155. | 1 |
| 38486485 | 2024 | FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma. | 1 |
| 38491348 | 2024 | The m(6)A modification mediated-lncRNA POU6F2-AS1 reprograms fatty acid metabolism and facilitates the growth of colorectal cancer via upregulation of FASN. | 0 |
| 38655619 | 2024 | DPP3 promotes breast cancer tumorigenesis by stabilizing FASN and promoting lipid synthesis. | 0 |
| 38667273 | 2024 | The Role of Fatty Acid Synthase in the Vascular Smooth Muscle Cell to Foam Cell Transition. | 0 |
| 38732103 | 2024 | Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth. | 0 |
| 38112617 | 2024 | FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-genomic Features of Prostate Cancer. | 0 |
| 38117249 | 2024 | The Regulation of Fatty Acid Synthase by Exosomal miR-143-5p and miR-342-5p in Idiopathic Pulmonary Fibrosis. | 1 |
| 38143182 | 2024 | FAS/SREBP-1c contributes to colorectal carcinogenesis through calcium signaling pathway and cAMP signaling pathway. | 0 |
| 38218866 | 2024 | Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer. | 2 |
Citation
Dessen P
FASN (fatty acid synthase)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40532/fasn
