Identity
HGNC
LOCATION
2q33.3
LOCUSID
ALIAS
COXPD44,KIAA0971
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22868
MIM: 612322
HGNC: 29160
Ensembl: ENSG00000118246
Variants:
dbSNP: 22868
ClinVar: 22868
TCGA: ENSG00000118246
COSMIC: FASTKD2
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35729327 | 2022 | A novel homozygous missense mutation in the FASTKD2 gene leads to Lennox-Gastaut syndrome. | 1 |
| 35729327 | 2022 | A novel homozygous missense mutation in the FASTKD2 gene leads to Lennox-Gastaut syndrome. | 1 |
| 31692063 | 2020 | FASTKD2 promotes cancer cell progression through upregulating Myc expression in pancreatic ductal adenocarcinoma. | 5 |
| 31944455 | 2020 | Mutations in FASTKD2 are associated with mitochondrial disease with multi-OXPHOS deficiency. | 14 |
| 31692063 | 2020 | FASTKD2 promotes cancer cell progression through upregulating Myc expression in pancreatic ductal adenocarcinoma. | 5 |
| 31944455 | 2020 | Mutations in FASTKD2 are associated with mitochondrial disease with multi-OXPHOS deficiency. | 14 |
| 29036396 | 2017 | The FASTK family of proteins: emerging regulators of mitochondrial RNA biology. | 41 |
| 29036396 | 2017 | The FASTK family of proteins: emerging regulators of mitochondrial RNA biology. | 41 |
| 25385369 | 2015 | FASTKD2 is associated with memory and hippocampal structure in older adults. | 27 |
| 26370583 | 2015 | FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation. | 51 |
| 25385369 | 2015 | FASTKD2 is associated with memory and hippocampal structure in older adults. | 27 |
| 26370583 | 2015 | FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation. | 51 |
| 25409762 | 2014 | Fas Activated Serine-Threonine Kinase Domains 2 (FASTKD2) mediates apoptosis of breast and prostate cancer cells through its novel FAST2 domain. | 11 |
| 25409762 | 2014 | Fas Activated Serine-Threonine Kinase Domains 2 (FASTKD2) mediates apoptosis of breast and prostate cancer cells through its novel FAST2 domain. | 11 |
| 21444724 | 2011 | A novel transcription complex that selectively modulates apoptosis of breast cancer cells through regulation of FASTKD2. | 39 |
Citation
Dessen P
FASTKD2 (FAST kinase domains 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-08-01
Online version: http://atlasgeneticsoncology.org/gene/52337/fastkd2
