Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23194
MIM: 605656
HGNC: 13604
Ensembl: ENSG00000183580
Variants:
dbSNP: 23194
ClinVar: 23194
TCGA: ENSG00000183580
COSMIC: FBXL7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183580 | ENST00000329673 | J3KNM9 |
| ENSG00000183580 | ENST00000504595 | Q9UJT9 |
| ENSG00000183580 | ENST00000510662 | Q9UJT9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35887149 | 2022 | FBXL7 Body Hypomethylation Is Frequent in Tumors from the Digestive and Respiratory Tracts and Is Associated with Risk-Factor Exposure. | 0 |
| 35887149 | 2022 | FBXL7 Body Hypomethylation Is Frequent in Tumors from the Digestive and Respiratory Tracts and Is Associated with Risk-Factor Exposure. | 0 |
| 34427826 | 2021 | 7-Ethoxyrosmanol alleviates hyperglycemia-induced vascular endothelial dysfunction by regulating FBXL7 expression. | 1 |
| 34427826 | 2021 | 7-Ethoxyrosmanol alleviates hyperglycemia-induced vascular endothelial dysfunction by regulating FBXL7 expression. | 1 |
| 31633297 | 2020 | Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome. | 8 |
| 32150671 | 2020 | miR-152-5p suppresses glioma progression and tumorigenesis and potentiates temozolomide sensitivity by targeting FBXL7. | 8 |
| 32839549 | 2020 | Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis. | 20 |
| 31633297 | 2020 | Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome. | 8 |
| 32150671 | 2020 | miR-152-5p suppresses glioma progression and tumorigenesis and potentiates temozolomide sensitivity by targeting FBXL7. | 8 |
| 32839549 | 2020 | Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis. | 20 |
| 25654763 | 2015 | F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7. | 22 |
| 25778398 | 2015 | The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin. | 40 |
| 25654763 | 2015 | F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7. | 22 |
| 25778398 | 2015 | The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin. | 40 |
| 22306998 | 2012 | Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest. | 35 |
Citation
Dessen P
FBXL7 (F-box and leucine rich repeat protein 7)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47427/fbxl7
