Identity
HGNC
LOCATION
1q23.3
LOCUSID
ALIAS
CD16,CD16A,CD16b,FCG3,FCGR3,FCGR3A,FCR-10,FCRIII,FCRIIIb
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2215
MIM: 610665
HGNC: 3620
Ensembl: ENSG00000162747
Variants:
dbSNP: 2215
ClinVar: 2215
TCGA: ENSG00000162747
COSMIC: FCGR3B
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443434 | Arthritis, Rheumatoid | Disease | MultilinkAnnotation | associated | 25966632 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36553504 | 2022 | Association of Fc Gamma Receptor 3B Gene Copy Number Variation with Rheumatoid Arthritis Susceptibility. | 0 |
| 36553504 | 2022 | Association of Fc Gamma Receptor 3B Gene Copy Number Variation with Rheumatoid Arthritis Susceptibility. | 0 |
| 34054821 | 2021 | The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils. | 2 |
| 34108956 | 2021 | FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene. | 1 |
| 34544201 | 2021 | Low-affinity immunoglobulin gamma Fc region receptor III-B (FcγRIIIB, CD16B) deficiency in patients with blood and immune system disorders. | 2 |
| 34551786 | 2021 | Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children. | 4 |
| 34054821 | 2021 | The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils. | 2 |
| 34108956 | 2021 | FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene. | 1 |
| 34544201 | 2021 | Low-affinity immunoglobulin gamma Fc region receptor III-B (FcγRIIIB, CD16B) deficiency in patients with blood and immune system disorders. | 2 |
| 34551786 | 2021 | Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children. | 4 |
| 32072650 | 2020 | Primary structure of human neutrophil antigens 1a and 1b. | 0 |
| 32375167 | 2020 | FCGR3B polymorphism predicts relapse risk in eosinophilic granulomatosis with polyangiitis. | 8 |
| 32739412 | 2020 | Aberrant FcγRIIb and FcγRIII expression on monocytes from patients with Behçet's disease. | 2 |
| 32922178 | 2020 | Lower HDL-C levels are associated with higher expressions of CD16 on monocyte subsets in coronary atherosclerosis. | 9 |
| 33163982 | 2020 | Single-cell analyses identify dysfunctional CD16(+) CD8 T cells in smokers. | 17 |
Citation
Dessen P
FCGR3B (Fc fragment of IgG receptor IIIb)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46575/fcgr3b
