FCN1 (ficolin 1)

2011-08-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
FCNM
FUSION GENES

Other Information

Locus ID:

NCBI: 2219
MIM: 601252
HGNC: 3623
Ensembl: ENSG00000085265

Variants:

dbSNP: 2219
ClinVar: 2219
TCGA: ENSG00000085265
COSMIC: FCN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000085265ENST00000371806O00602
ENSG00000085265ENST00000616356A0A087WVE2

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Complement cascadeREACTOMER-HSA-166658
Initial triggering of complementREACTOMER-HSA-166663
Creation of C4 and C2 activatorsREACTOMER-HSA-166786
Lectin pathway of complement activationREACTOMER-HSA-166662
Ficolins bind to repetitive carbohydrate structures on the target cell surfaceREACTOMER-HSA-2855086
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379968692023Increased expression of ficolin-1 is associated with airway obstruction in asthma.0
379968692023Increased expression of ficolin-1 is associated with airway obstruction in asthma.0
336000132022FCN1 polymorphisms are not the markers of dental caries susceptibility in Polish children: A case-control study.2
342123202022Increased Levels of serum Pentraxin 3 in Critical Coronavirus Disease-2019 Patients.9
346864942022M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis.0
336000132022FCN1 polymorphisms are not the markers of dental caries susceptibility in Polish children: A case-control study.2
342123202022Increased Levels of serum Pentraxin 3 in Critical Coronavirus Disease-2019 Patients.9
346864942022M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis.0
335915732021Association of ficolin-1 and ficolin-3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population.2
335915732021Association of ficolin-1 and ficolin-3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population.2
321422112020Ficolin-1 gene (FCN1) -144 C/A polymorphism is associated with adverse outcome of severe pneumonia in the under-five Egyptian children: A multicenter study.2
326013702020Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults.11
329157972020Association between serum ficolin-1 level and disease progression in primary biliary cholangitis.3
321422112020Ficolin-1 gene (FCN1) -144 C/A polymorphism is associated with adverse outcome of severe pneumonia in the under-five Egyptian children: A multicenter study.2
326013702020Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults.11

Citation

Dessen P

FCN1 (ficolin 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52302/fcn1