Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2243
MIM: 134820
HGNC: 3661
Ensembl: ENSG00000171560
Variants:
dbSNP: 2243
ClinVar: 2243
TCGA: ENSG00000171560
COSMIC: FGA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171560 | ENST00000403106 | P02671 |
| ENSG00000171560 | ENST00000622532 | A0A087WUA0 |
| ENSG00000171560 | ENST00000651975 | P02671 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448006 | abciximab | Chemical | Pathway | associated | 20938371 | ||
| PA449483 | eptifibatide | Chemical | Pathway | associated | 20938371 | ||
| PA451698 | tirofiban | Chemical | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36599322 | 2023 | Two Novel Heterozygous Mutations (p.γPhe230Val and p.AαAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families. | 0 |
| 36856592 | 2023 | Fibrinogen-Aα THR312ALA Polymorphism is Associated to Chronic Thromboembolic Pulmonary Hypertension in Turkey. | 0 |
| 36933991 | 2023 | Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients. | 4 |
| 37823427 | 2023 | Fibrinogen Aα gene genotyping in patients with inherited afibrinogenemia deficiency; a novel mutation in Iranian afibrinogenemia patients. | 0 |
| 37906135 | 2023 | [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene]. | 0 |
| 36599322 | 2023 | Two Novel Heterozygous Mutations (p.γPhe230Val and p.AαAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families. | 0 |
| 36856592 | 2023 | Fibrinogen-Aα THR312ALA Polymorphism is Associated to Chronic Thromboembolic Pulmonary Hypertension in Turkey. | 0 |
| 36933991 | 2023 | Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients. | 4 |
| 37823427 | 2023 | Fibrinogen Aα gene genotyping in patients with inherited afibrinogenemia deficiency; a novel mutation in Iranian afibrinogenemia patients. | 0 |
| 37906135 | 2023 | [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene]. | 0 |
| 35498401 | 2022 | FGA Controls VEGFA Secretion to Promote Angiogenesis by Activating the VEGFR2-FAK Signalling Pathway. | 12 |
| 35498401 | 2022 | FGA Controls VEGFA Secretion to Promote Angiogenesis by Activating the VEGFR2-FAK Signalling Pathway. | 12 |
| 32877852 | 2021 | Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders. | 0 |
| 33472402 | 2021 | GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen αC-Region. | 11 |
| 33901106 | 2021 | Identification of a novel mutation in congenital afibrinogenemia in Iranian patients. | 1 |
Citation
Dessen P
FGA (fibrinogen alpha chain)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45994/fga
