Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2244
MIM: 134830
HGNC: 3662
Ensembl: ENSG00000171564
Variants:
dbSNP: 2244
ClinVar: 2244
TCGA: ENSG00000171564
COSMIC: FGB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171564 | ENST00000302068 | P02675 |
| ENSG00000171564 | ENST00000302068 | V9HVY1 |
| ENSG00000171564 | ENST00000425838 | F8W6P4 |
| ENSG00000171564 | ENST00000509493 | D6REL8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448006 | abciximab | Chemical | Pathway | associated | 20938371 | ||
| PA449483 | eptifibatide | Chemical | Pathway | associated | 20938371 | ||
| PA451698 | tirofiban | Chemical | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35972516 | 2023 | The role of fibrinogen in traumatic brain injury: from molecular pathological mechanisms to clinical management. | 3 |
| 36933991 | 2023 | Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients. | 4 |
| 36990158 | 2023 | Glycoprotein VI interplay with fibrin(ogen) in thrombosis. | 2 |
| 37119127 | 2023 | Impact of Fibrinogen, Fibrin Thrombi, and Thrombin on Cancer Cell Extravasation Using In Vitro Microvascular Networks. | 4 |
| 37186763 | 2023 | Evaluating the Association Between Fibrinogen and Rotational Thromboelastometry and the Progression to Severe Obstetric Hemorrhage. | 0 |
| 37442896 | 2023 | Pathogenic Role of Fibrinogen in the Neuropathology of Multiple Sclerosis: A Tale of Sorrows and Fears. | 4 |
| 37481624 | 2023 | Association between fibrinogen level and length of stay in patients with lower extremity atherosclerotic disease: a retrospective cohort study. | 0 |
| 37516116 | 2023 | A Novel Fibrinogen Mutation p.BβAla68Asp Causes an Inherited Dysfibrinogenemia. | 0 |
| 37517272 | 2023 | Association between lipoprotein(a) and ischemic stroke: Fibrinogen as a mediator. | 1 |
| 37906135 | 2023 | [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene]. | 0 |
| 35972516 | 2023 | The role of fibrinogen in traumatic brain injury: from molecular pathological mechanisms to clinical management. | 3 |
| 36933991 | 2023 | Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients. | 4 |
| 36990158 | 2023 | Glycoprotein VI interplay with fibrin(ogen) in thrombosis. | 2 |
| 37119127 | 2023 | Impact of Fibrinogen, Fibrin Thrombi, and Thrombin on Cancer Cell Extravasation Using In Vitro Microvascular Networks. | 4 |
| 37186763 | 2023 | Evaluating the Association Between Fibrinogen and Rotational Thromboelastometry and the Progression to Severe Obstetric Hemorrhage. | 0 |
Citation
Dessen P
FGB (fibrinogen beta chain)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40548/fgb
