FGL1 (fibrinogen like 1)

2003-06-01 Affiliation

Identity

HGNC

FGL1

LOCATION

8p22

LOCUSID

2267

ALIAS

HFREP1,HP-041,HPS,LFIRE-1,LFIRE1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 2267
MIM: 605776
HGNC: 3695
Ensembl: ENSG00000104760

Variants:

dbSNP: 2267
ClinVar: 2267
TCGA: ENSG00000104760
COSMIC: FGL1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000104760	ENST00000381840	Q08830
ENSG00000104760	ENST00000381841	Q08830
ENSG00000104760	ENST00000398054	Q08830
ENSG00000104760	ENST00000398056	Q08830
ENSG00000104760	ENST00000427924	Q08830
ENSG00000104760	ENST00000518650	Q08830
ENSG00000104760	ENST00000522444	Q08830

Expression (GTEx)

500

1000

1500

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
15063762	2004	Genetic variations in humans associated with differences in the course of hepatitis C.	16
14981537	2004	LFIRE-1/HFREP-1, a liver-specific gene, is frequently downregulated and has growth suppressor activity in hepatocellular carcinoma.	15
18039467	2008	Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant.	13
20800603	2010	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	12
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
16996032	2006	Hepatocyte-derived fibrinogen-related protein-1 is associated with the fibrin matrix of a plasma clot.	9
19304666	2009	Specific expression and regulation of hepassocin in the liver and down-regulation of the correlation of HNF1alpha with decreased levels of hepassocin in human hepatocellular carcinoma.	8
21618590	2011	Hepassocin regulates cell proliferation of the human hepatic cells L02 and hepatocarcinoma cells through different mechanisms.	8

Citation

Dessen P

FGL1 (fibrinogen like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40571/fgl1