Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10875
MIM: 605351
HGNC: 3696
Ensembl: ENSG00000127951
Variants:
dbSNP: 10875
ClinVar: 10875
TCGA: ENSG00000127951
COSMIC: FGL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000127951 | ENST00000248598 | Q14314 |
| ENSG00000127951 | ENST00000248598 | A4D1B8 |
| ENSG00000127951 | ENST00000637771 | A0A1B0GVK0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38902261 | 2024 | CD8(+) T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB. | 0 |
| 38902261 | 2024 | CD8(+) T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB. | 0 |
| 36243222 | 2023 | A homozygous truncating mutation of FGL2 is associated with immune dysregulation. | 0 |
| 37200306 | 2023 | Presence and activity of Fibrinogen like protein 2 in platelets. | 0 |
| 36243222 | 2023 | A homozygous truncating mutation of FGL2 is associated with immune dysregulation. | 0 |
| 37200306 | 2023 | Presence and activity of Fibrinogen like protein 2 in platelets. | 0 |
| 35029030 | 2022 | Fibrinogen-like protein 2 in gastrointestinal stromal tumour. | 4 |
| 36671474 | 2022 | Assessment of Fibrinogen-like 2 (FGL2) in Human Chronic Kidney Disease through Transcriptomics Data Analysis. | 2 |
| 35029030 | 2022 | Fibrinogen-like protein 2 in gastrointestinal stromal tumour. | 4 |
| 36671474 | 2022 | Assessment of Fibrinogen-like 2 (FGL2) in Human Chronic Kidney Disease through Transcriptomics Data Analysis. | 2 |
| 33754059 | 2021 | Dabigatran activates inflammation resolution by promoting fibrinogen-like protein 2 shedding and RvD5(n-3 DPA) production. | 4 |
| 33893391 | 2021 | Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu. | 16 |
| 34109427 | 2021 | Soluble fibrinogen‑like protein 2 levels are decreased in patients with ischemic heart failure and associated with cardiac function. | 1 |
| 34154648 | 2021 | Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population. | 5 |
| 33754059 | 2021 | Dabigatran activates inflammation resolution by promoting fibrinogen-like protein 2 shedding and RvD5(n-3 DPA) production. | 4 |
Citation
Dessen P
FGL2 (fibrinogen like 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50707/fgl2
