FIGNL1 (fidgetin like 1)

2013-09-01  

Identity

HGNC
LOCATION
7p12.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 63979
MIM: 615383
HGNC: 13286
Ensembl: ENSG00000132436

Variants:

dbSNP: 63979
ClinVar: 63979
TCGA: ENSG00000132436
COSMIC: FIGNL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132436ENST00000356889Q6PIW4
ENSG00000132436ENST00000395556Q6PIW4
ENSG00000132436ENST00000419119Q6PIW4
ENSG00000132436ENST00000420829C9JTG6
ENSG00000132436ENST00000422854C9JHJ4
ENSG00000132436ENST00000433017Q6PIW4
ENSG00000132436ENST00000435566C9JSC4
ENSG00000132436ENST00000436590C9JKI6
ENSG00000132436ENST00000440350C9JTB2
ENSG00000132436ENST00000448788C9JP37
ENSG00000132436ENST00000611938Q6PIW4
ENSG00000132436ENST00000613602Q6PIW4
ENSG00000132436ENST00000615084Q6PIW4
ENSG00000132436ENST00000617389Q6PIW4

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190587892009A common variant in DRD3 receptor is associated with autism spectrum disorder.19
237543762013FIGNL1-containing protein complex is required for efficient homologous recombination repair.18
273844582016Fidgetin-like 1 is a ciliogenesis-inhibitory centrosome protein.4
309267762019Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase.4
282600652017FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide.2
315410152019FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation.1

Citation

Dessen P

FIGNL1 (fidgetin like 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-09-01

Online version: http://atlasgeneticsoncology.org/gene/53507/fignl1