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FILIP1L (filamin A interacting protein 1 like)

Identity

Alias_symbol (synonym)DOC-1
GIP130
Other aliasDOC1
GIP90
HGNC (Hugo) FILIP1L
LocusID (NCBI) 11259
Atlas_Id 40353
Location 3q12.1  [Link to chromosome band 3q12]
Location_base_pair Starts at 99833144 and ends at 100114513 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ALPL (1p36.12) / FILIP1L (3q12.1)FILIP1L (3q12.1) / IMPG2 (3q12.3)ALPL 1p36.12 / FILIP1L 3q12.1
FILIP1L 3q12.1 / IMPG2 3q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(1;3)(p36;q12) ALPL/FILIP1L
FILIP1L/IMPG2 (3q12)

External links

Nomenclature
HGNC (Hugo)FILIP1L   24589
Cards
Entrez_Gene (NCBI)FILIP1L  11259  filamin A interacting protein 1 like
AliasesDOC-1; DOC1; GIP130; GIP90
GeneCards (Weizmann)FILIP1L
Ensembl hg19 (Hinxton)ENSG00000168386 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168386 [Gene_View]  ENSG00000168386 [Sequence]  chr3:99833144-100114513 [Contig_View]  FILIP1L [Vega]
ICGC DataPortalENSG00000168386
TCGA cBioPortalFILIP1L
AceView (NCBI)FILIP1L
Genatlas (Paris)FILIP1L
WikiGenes11259
SOURCE (Princeton)FILIP1L
Genetics Home Reference (NIH)FILIP1L
Genomic and cartography
GoldenPath hg38 (UCSC)FILIP1L  -     chr3:99833144-100114513 -  3q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FILIP1L  -     3q12.1   [Description]    (hg19-Feb_2009)
GoldenPathFILIP1L - 3q12.1 [CytoView hg19]  FILIP1L - 3q12.1 [CytoView hg38]
ImmunoBaseENSG00000168386
Mapping of homologs : NCBIFILIP1L [Mapview hg19]  FILIP1L [Mapview hg38]
OMIM612993   
Gene and transcription
Genbank (Entrez)AF329092 AF514867 AF514868 AF514869 AK096195
RefSeq transcript (Entrez)NM_001042459 NM_001282793 NM_001282794 NM_001370247 NM_014890 NM_182909
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FILIP1L
Cluster EST : UnigeneHs.104672 [ NCBI ]
CGAP (NCI)Hs.104672
Alternative Splicing GalleryENSG00000168386
Gene ExpressionFILIP1L [ NCBI-GEO ]   FILIP1L [ EBI - ARRAY_EXPRESS ]   FILIP1L [ SEEK ]   FILIP1L [ MEM ]
Gene Expression Viewer (FireBrowse)FILIP1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11259
GTEX Portal (Tissue expression)FILIP1L
Human Protein AtlasENSG00000168386-FILIP1L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ4L180   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ4L180  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ4L180
Splice isoforms : SwissVarQ4L180
PhosPhoSitePlusQ4L180
Domains : Interpro (EBI)Cortactin-binding_p2_N   
Domain families : Pfam (Sanger)CortBP2 (PF09727)   
Domain families : Pfam (NCBI)pfam09727   
Conserved Domain (NCBI)FILIP1L
DMDM Disease mutations11259
Blocks (Seattle)FILIP1L
SuperfamilyQ4L180
Human Protein Atlas [tissue]ENSG00000168386-FILIP1L [tissue]
Peptide AtlasQ4L180
HPRD16832
IPIIPI00297578   IPI00477324   IPI00748547   IPI00658170   IPI00877049   IPI00922613   IPI00922540   IPI00953441   IPI00946195   
Protein Interaction databases
DIP (DOE-UCLA)Q4L180
IntAct (EBI)Q4L180
FunCoupENSG00000168386
BioGRIDFILIP1L
STRING (EMBL)FILIP1L
ZODIACFILIP1L
Ontologies - Pathways
QuickGOQ4L180
Ontology : AmiGOmolecular_function  nucleus  cytoplasm  biological_process  membrane  
Ontology : EGO-EBImolecular_function  nucleus  cytoplasm  biological_process  membrane  
NDEx NetworkFILIP1L
Atlas of Cancer Signalling NetworkFILIP1L
Wikipedia pathwaysFILIP1L
Orthology - Evolution
OrthoDB11259
GeneTree (enSembl)ENSG00000168386
Phylogenetic Trees/Animal Genes : TreeFamFILIP1L
HOGENOMQ4L180
Homologs : HomoloGeneFILIP1L
Homology/Alignments : Family Browser (UCSC)FILIP1L
Gene fusions - Rearrangements
Fusion : MitelmanALPL/FILIP1L [1p36.12/3q12.1]  [t(1;3)(p36;q12)]  
Fusion : MitelmanFILIP1L/IMPG2 [3q12.1/3q12.3]  [t(3;3)(q12;q12)]  
Fusion PortalALPL 1p36.12 FILIP1L 3q12.1 BRCA
Fusion PortalFILIP1L 3q12.1 IMPG2 3q12.3 HNSC
Fusion : QuiverFILIP1L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFILIP1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FILIP1L
dbVarFILIP1L
ClinVarFILIP1L
1000_GenomesFILIP1L 
Exome Variant ServerFILIP1L
ExAC (Exome Aggregation Consortium)ENSG00000168386
GNOMAD BrowserENSG00000168386
Varsome BrowserFILIP1L
Genetic variants : HAPMAP11259
Genomic Variants (DGV)FILIP1L [DGVbeta]
DECIPHERFILIP1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFILIP1L 
Mutations
ICGC Data PortalFILIP1L 
TCGA Data PortalFILIP1L 
Broad Tumor PortalFILIP1L
OASIS PortalFILIP1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFILIP1L  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFILIP1L
Mutations and Diseases : HGMDFILIP1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FILIP1L
DgiDB (Drug Gene Interaction Database)FILIP1L
DoCM (Curated mutations)FILIP1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FILIP1L (select a term)
intoGenFILIP1L
Cancer3DFILIP1L(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612993   
Orphanet
DisGeNETFILIP1L
MedgenFILIP1L
Genetic Testing Registry FILIP1L
NextProtQ4L180 [Medical]
TSGene11259
GENETestsFILIP1L
Target ValidationFILIP1L
Huge Navigator FILIP1L [HugePedia]
snp3D : Map Gene to Disease11259
BioCentury BCIQFILIP1L
ClinGenFILIP1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11259
Chemical/Pharm GKB GenePA162388580
Clinical trialFILIP1L
Miscellaneous
canSAR (ICR)FILIP1L (select the gene name)
DataMed IndexFILIP1L
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFILIP1L
EVEXFILIP1L
GoPubMedFILIP1L
iHOPFILIP1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Nov 13 17:43:32 CET 2019
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