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FLI1 (Friend leukemia virus integration 1)

Identity

Other namesEWSR2
SIC-1
HGNC (Hugo) FLI1
Location 11q24.3
Location_base_pair Starts at 128069023 and ends at 128188372 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FLI1   3749
Entrez_Gene (NCBI)FLI1  2313  Friend leukemia virus integration 1
Cards
GeneCards (Weizmann)FLI1
Ensembl (Hinxton)ENSG00000151702 [Gene_View]  FLI1 [Vega]
AceView (NCBI)FLI1
Genatlas (Paris)FLI1
euGene (Indiana)2313
SOURCE (Stanford)NM_001167681 NM_002017
Gene Expression (Array Express) ENSG00000151702
Genomic and cartography
GoldenPath (UCSC)FLI1  -  11q24.3   chr11:128069023-128188372 +  11q24.3   [Description]    (hg18-March_2006)
EnsemblFLI1 - 11q24.3 [CytoView]
Mapping of homologs : NCBIFLI1 [Mapview]
OMIM193067   
Gene and transcription
Gene : Genbank (Entrez)AF147318 AI354789 AK294279 AK300153 AK313370
Reference sequence (RefSeq transcript) :SRSNM_001167681 NM_002017
Reference transcript : EntrezNM_001167681 NM_002017
RefSeq genomic : SRSAC_000054 AC_000143 NC_000011 NT_033899 NW_001838044 NW_925173
RefSeq genomic : EntrezAC_000054 AC_000143 NC_000011 NT_033899 NW_001838044 NW_925173
Consensus coding sequences : CCDS NCBIFLI1
Cluster EST : UnigeneHs.504281 [ SRS ] Hs.504281 [ NCBI ]
Alternative Splicing : Fast-db (Paris)15058
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ01543 (SRS) Q01543 (Expasy) Q01543 (Uniprot)
With graphics : InterProQ01543
Splice isoforms : VarSplice FASTAQ01543(VarSplice FASTA)
Domaine pattern : Prosite (SRS)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)    PNT (PS51433)   
Domain pattern : Prosite (Expaxy)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)    PNT (PS51433)   
Domains : Interpro (SRS)Ets    SAM_homology    SAM_PNT    SAM_type    Wing_hlx_DNA_bd   
Domains : Interpro (EBI)Ets    SAM_homology    SAM_PNT    SAM_type    Wing_hlx_DNA_bd   
Related proteins : CluSTrQ01543
Domain families : Pfam SRSEts (PF00178)    SAM_PNT (PF02198)   
Domain families : Pfam SangerEts (PF00178)    SAM_PNT (PF02198)   
Domain families : Pfam NCBIpfam00178    pfam02198   
Domain families : Smart EMBLETS (SM00413)  SAM_PNT (SM00251)  
Blocks (Seattle)Q01543
Crystal structure of protein : PDB SRS1FLI    1X66    2YTU   
Crystal structure of protein : PDBSum1FLI    1X66    2YTU   
Crystal structure of protein : IMB1FLI    1X66    2YTU   
Crystal structure of protein : PDB RSDB1FLI    1X66    2YTU   
HPRD01901
Protein Interaction databases
DIP (DOE-UCLA)Q01543
IntAct (EBI)Q01543
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIFLI1
SNP : GeneSNP UtahFLI1
SNP : HGBaseFLI1
Genetic variants : HAPMAPFLI1
Cancer Gene: CensusFLI1 
Somatic Mutations in Cancer : COSMICFLI1 
Rearrangement : COSMICEWSR1 22q12.2  -  FLI1 11q24.3
Translocation Breakpoints in Cancer : TICdbtranscription 
Mutations and Diseases : HGMDFLI1
Hereditary diseases : OMIM193067   
Hereditary diseases : GENETests193067   
Diseases : Genetic AssociationFLI1
General knowledge
Homologs : HomoloGeneFLI1
Homology/Alignments : Family Browser UCSCFLI1
Phylogenetic Trees/Animal Genes : TreeFamFLI1
Chemical/Protein Interactions : CTD2313
Keywords Ontology : AmiGOtranscription factor activity  protein binding  nucleus  regulation of transcription, DNA-dependent  hemostasis  blood circulation  organ morphogenesis  sequence-specific DNA binding  
Keywords Ontology : EGO-EBItranscription factor activity  protein binding  nucleus  regulation of transcription, DNA-dependent  hemostasis  blood circulation  organ morphogenesis  sequence-specific DNA binding  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesFLI1 Related clones (RZPD - Berlin)
Literature
PubMed55 Pubmed reference(s) in Entrez
PubGeneFLI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:38:18 CET 2010
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