FLOT2 (flotillin 2)

2007-02-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
ECS-1,ECS1,ESA,ESA1,M17S1
FUSION GENES

Other Information

Locus ID:

NCBI: 2319
MIM: 131560
HGNC: 3758
Ensembl: ENSG00000132589

Variants:

dbSNP: 2319
ClinVar: 2319
TCGA: ENSG00000132589
COSMIC: FLOT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132589ENST00000394906E7EMK3
ENSG00000132589ENST00000394908Q14254
ENSG00000132589ENST00000394908A0A024QZ62
ENSG00000132589ENST00000465427K7EKW9
ENSG00000132589ENST00000580805J3QKZ4
ENSG00000132589ENST00000585169J3QLD9
ENSG00000132589ENST00000586827K7EJ47

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450

Pathways

PathwaySourceExternal ID
Insulin signaling pathwayKEGGko04910
Insulin signaling pathwayKEGGhsa04910
Neuronal SystemREACTOMER-HSA-112316
SALM protein interactions at the synapsesREACTOMER-HSA-8849932
Protein-protein interactions at synapsesREACTOMER-HSA-6794362

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385318032024Analysis and Investigation of Bioinformatics and Epigenetics Reveal the Underlying Mechanisms by which FLOT2 Modulates the Progression of Diffuse Large B-cell Lymphoma.0
385318032024Analysis and Investigation of Bioinformatics and Epigenetics Reveal the Underlying Mechanisms by which FLOT2 Modulates the Progression of Diffuse Large B-cell Lymphoma.0
364704252023Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth.1
378806122023EFR3A: a new raft domain organizing protein?0
364704252023Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth.1
378806122023EFR3A: a new raft domain organizing protein?0
342542812022N6-methyladenosine Demethylase FTO Induces the Dysfunctions of Ovarian Granulosa Cells by Upregulating Flotillin 2.10
349306752022MicroRNA-486-3p promotes the proliferation and metastasis of cutaneous squamous cell carcinoma by suppressing flotillin-2.2
352986132022The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia.5
358726272022FLOT2 Promotes the Proliferation and Epithelial-mesenchymal Transition of Cervical Cancer by Activating the MEK/ERK1/2 Pathway.1
342542812022N6-methyladenosine Demethylase FTO Induces the Dysfunctions of Ovarian Granulosa Cells by Upregulating Flotillin 2.10
349306752022MicroRNA-486-3p promotes the proliferation and metastasis of cutaneous squamous cell carcinoma by suppressing flotillin-2.2
352986132022The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia.5
358726272022FLOT2 Promotes the Proliferation and Epithelial-mesenchymal Transition of Cervical Cancer by Activating the MEK/ERK1/2 Pathway.1
336316762021FLOT2 upregulation promotes growth and invasion by interacting and stabilizing EphA2 in gliomas.9

Citation

Dessen P

FLOT2 (flotillin 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46114/flot2