FMO4 (flavin containing dimethylaniline monoxygenase 4)

2007-04-01  

Identity

HGNC
LOCATION
1q24.3
LOCUSID
ALIAS
FMO2
FUSION GENES

Other Information

Locus ID:

NCBI: 2329
MIM: 136131
HGNC: 3772
Ensembl: ENSG00000076258

Variants:

dbSNP: 2329
ClinVar: 2329
TCGA: ENSG00000076258
COSMIC: FMO4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000076258ENST00000367749P31512

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Drug metabolism - cytochrome P450KEGGko00982
Drug metabolism - cytochrome P450KEGGhsa00982

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198984822009Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.84
205297632010Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.8
193074492009Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and human liver and kidney microsomes.4

Citation

Dessen P

FMO4 (flavin containing dimethylaniline monoxygenase 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46842/fmo4