| Nomenclature |
|---|
| HGNC (Hugo) | FOXD3 3804 |
| Cards |
|---|
| Entrez_Gene (NCBI) | FOXD3 27022 forkhead box D3 |
| Aliases | AIS1; Genesis; HFH2; VAMAS2 |
| GeneCards (Weizmann) | FOXD3 |
| Ensembl hg19 (Hinxton) | ENSG00000187140 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000187140 [Gene_View] ENSG00000187140 [Sequence] chr1:63323059-63325126 [Contig_View] FOXD3 [Vega] |
| ICGC DataPortal | ENSG00000187140 |
| TCGA cBioPortal | FOXD3 |
| AceView (NCBI) | FOXD3 |
| Genatlas (Paris) | FOXD3 |
| WikiGenes | 27022 |
| SOURCE (Princeton) | FOXD3 |
| Genetics Home Reference (NIH) | FOXD3 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | FOXD3 - chr1:63323059-63325126 + 1p31.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | FOXD3 - 1p31.3 [Description] (hg19-Feb_2009) |
| GoldenPath | FOXD3 - 1p31.3 [CytoView hg19] FOXD3 - 1p31.3 [CytoView hg38] |
| ImmunoBase | ENSG00000187140 |
| Mapping of homologs : NCBI | FOXD3 [Mapview hg19] FOXD3 [Mapview hg38] |
| OMIM | 607836 611539 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF086235 L12142 |
| RefSeq transcript (Entrez) | NM_012183 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | FOXD3 |
| Cluster EST : Unigene | Hs.546573 [ NCBI ] |
| CGAP (NCI) | Hs.546573 |
| Alternative Splicing Gallery | ENSG00000187140 |
| Gene Expression | FOXD3 [ NCBI-GEO ] FOXD3 [ EBI - ARRAY_EXPRESS ]
FOXD3 [ SEEK ] FOXD3 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | FOXD3 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 27022 |
| GTEX Portal (Tissue expression) | FOXD3 |
| Human Protein Atlas | ENSG00000187140-FOXD3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q9UJU5 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q9UJU5 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q9UJU5 |
| Splice isoforms : SwissVar | Q9UJU5 |
| PhosPhoSitePlus | Q9UJU5 |
| Domaine pattern : Prosite (Expaxy) | FORK_HEAD_1 (PS00657) FORK_HEAD_2 (PS00658) FORK_HEAD_3 (PS50039) |
| Domains : Interpro (EBI) | Fork_head_dom TF_fork_head_CS_1 TF_fork_head_CS_2 WH-like_DNA-bd_sf WH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | Forkhead (PF00250) |
| Domain families : Pfam (NCBI) | pfam00250 |
| Domain families : Smart (EMBL) | FH (SM00339) |
| Conserved Domain (NCBI) | FOXD3 |
| DMDM Disease mutations | 27022 |
| Blocks (Seattle) | FOXD3 |
| Superfamily | Q9UJU5 |
| Human Protein Atlas [tissue] | ENSG00000187140-FOXD3 [tissue] |
| Peptide Atlas | Q9UJU5 |
| HPRD | 07018 |
| IPI | IPI00007164 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q9UJU5 |
| IntAct (EBI) | Q9UJU5 |
| FunCoup | ENSG00000187140 |
| BioGRID | FOXD3 |
| STRING (EMBL) | FOXD3 |
| ZODIAC | FOXD3 |
| Ontologies - Pathways |
|---|
| QuickGO | Q9UJU5 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific in utero embryonic development DNA-binding transcription factor activity protein binding nucleus nucleoplasm regulation of transcription by RNA polymerase II anatomical structure morphogenesis cell differentiation somatic stem cell population maintenance positive regulation of transcription by RNA polymerase II |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific in utero embryonic development DNA-binding transcription factor activity protein binding nucleus nucleoplasm regulation of transcription by RNA polymerase II anatomical structure morphogenesis cell differentiation somatic stem cell population maintenance positive regulation of transcription by RNA polymerase II |
| NDEx Network | FOXD3 |
| Atlas of Cancer Signalling Network | FOXD3 |
| Wikipedia pathways | FOXD3 |
| Orthology - Evolution |
|---|
| OrthoDB | 27022 |
| GeneTree (enSembl) | ENSG00000187140 |
| Phylogenetic Trees/Animal Genes : TreeFam | FOXD3 |
| HOGENOM | Q9UJU5 |
| Homologs : HomoloGene | FOXD3 |
| Homology/Alignments : Family Browser (UCSC) | FOXD3 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | FOXD3 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | FOXD3 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | FOXD3 |
| dbVar | FOXD3 |
| ClinVar | FOXD3 |
| 1000_Genomes | FOXD3 |
| Exome Variant Server | FOXD3 |
| ExAC (Exome Aggregation Consortium) | ENSG00000187140 |
| GNOMAD Browser | ENSG00000187140 |
| Varsome Browser | FOXD3 |
| Genetic variants : HAPMAP | 27022 |
| Genomic Variants (DGV) | FOXD3 [DGVbeta] |
| DECIPHER | FOXD3 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | FOXD3 |
| Mutations |
|---|
| ICGC Data Portal | FOXD3 |
| TCGA Data Portal | FOXD3 |
| Broad Tumor Portal | FOXD3 |
| OASIS Portal | FOXD3 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | FOXD3 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | FOXD3 |
| Mutations and Diseases : HGMD | FOXD3 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search FOXD3 |
| DgiDB (Drug Gene Interaction Database) | FOXD3 |
| DoCM (Curated mutations) | FOXD3 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | FOXD3 (select a term) |
| intoGen | FOXD3 |
| Cancer3D | FOXD3(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 607836 611539 |
| Orphanet | 19560 |
| DisGeNET | FOXD3 |
| Medgen | FOXD3 |
| Genetic Testing Registry | FOXD3
|
| NextProt | Q9UJU5 [Medical] |
| TSGene | 27022 |
| GENETests | FOXD3 |
| Target Validation | FOXD3 |
| Huge Navigator |
FOXD3 [HugePedia] |
| snp3D : Map Gene to Disease | 27022 |
| BioCentury BCIQ | FOXD3 |
| ClinGen | FOXD3 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 27022 |
| Chemical/Pharm GKB Gene | PA28221 |
| Clinical trial | FOXD3 |
| Miscellaneous |
|---|
| canSAR (ICR) | FOXD3 (select the gene name) |
| DataMed Index | FOXD3 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 39 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | FOXD3 |
| EVEX | FOXD3 |
| GoPubMed | FOXD3 |
| iHOP | FOXD3 |
