FOXF2 (forkhead box F2)

2007-04-01  

Identity

HGNC
LOCATION
6p25.3
LOCUSID
ALIAS
FKHL6,FREAC-2,FREAC2

Other Information

Locus ID:

NCBI: 2295
MIM: 603250
HGNC: 3810
Ensembl: ENSG00000137273

Variants:

dbSNP: 2295
ClinVar: 2295
TCGA: ENSG00000137273
COSMIC: FOXF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137273ENST00000645481Q12947

Expression (GTEx)

0
50
100
150
200

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164712499Antithyroid PreparationsChemicalClinicalAnnotation, VariantAnnotationassociatedPD27157822
PA443297AgranulocytosisDiseaseClinicalAnnotation, VariantAnnotationassociatedPD27157822

References

Pubmed IDYearTitleCitations
233832072013MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer.57
257988332016The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers.54
270685882016Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.45
261200302015Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier.30
257385202015miR-182 promotes cell growth and invasion by targeting forkhead box F2 transcription factor in colorectal cancer.24
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
195627242009The FOXF2 pathway in the human prostate stroma.15
285069912017Sonic hedgehog regulation of <i>Foxf2</i> promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.13
260705602015DNA Methylation Affects the SP1-regulated Transcription of FOXF2 in Breast Cancer Cells.12
293740642018Forkhead Box F2 Suppresses Gastric Cancer through a Novel FOXF2-IRF2BPL-β-Catenin Signaling Axis.12

Citation

Dessen P

FOXF2 (forkhead box F2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47064/foxf2