FOXL1 (forkhead box L1)

2007-04-01  

Identity

HGNC
LOCATION
16q24.1
LOCUSID
ALIAS
FKH6,FKHL11,FREAC7

Other Information

Locus ID:

NCBI: 2300
MIM: 603252
HGNC: 3817
Ensembl: ENSG00000176678

Variants:

dbSNP: 2300
ClinVar: 2300
TCGA: ENSG00000176678
COSMIC: FOXL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176678ENST00000320241Q12952
ENSG00000176678ENST00000593625M0R279

Expression (GTEx)

0
5
10
15
20
25
30

References

Pubmed IDYearTitleCitations
214572322012Identification of de novo mutations and rare variants in hypoplastic left heart syndrome.33
201986512010Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers.19
185649212008Candidate gene analysis in primary lymphedema.16
309712902019Long noncoding RNA EPB41L4A-AS2 inhibits hepatocellular carcinoma development by sponging miR-301a-5p and targeting FOXL1.13
215365452011FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1.11
250106792014Forkhead box L1 is frequently downregulated in gallbladder cancer and inhibits cell growth through apoptosis induction by mitochondrial dysfunction.8
260629772015Inhibitory effects of forkhead box L1 gene on osteosarcoma growth through the induction of cell cycle arrest and apoptosis.7
244273312014Foxl1 inhibits tumor invasion and predicts outcome in human renal cancer.5
279385072017Overexpression of Forkhead Box L1 (FOXL1) Inhibits the Proliferation and Invasion of Breast Cancer Cells.4
269606892016Low level of FOXL1 indicates a worse prognosis for gastric cancer patients.1

Citation

Dessen P

FOXL1 (forkhead box L1)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47339/foxl1