| Nomenclature |
|---|
| HGNC (Hugo) | FOXN1 12765 |
| LRG (Locus Reference Genomic) | LRG_61 |
| Cards |
|---|
| Entrez_Gene (NCBI) | FOXN1 8456 forkhead box N1 |
| Aliases | FKHL20; RONU; WHN |
| GeneCards (Weizmann) | FOXN1 |
| Ensembl hg19 (Hinxton) | ENSG00000109101 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000109101 [Gene_View] ENSG00000109101 [Sequence] chr17:28523941-28538157 [Contig_View] FOXN1 [Vega] |
| ICGC DataPortal | ENSG00000109101 |
| TCGA cBioPortal | FOXN1 |
| AceView (NCBI) | FOXN1 |
| Genatlas (Paris) | FOXN1 |
| WikiGenes | 8456 |
| SOURCE (Princeton) | FOXN1 |
| Genetics Home Reference (NIH) | FOXN1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | FOXN1 - chr17:28523941-28538157 + 17q11.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | FOXN1 - 17q11.2 [Description] (hg19-Feb_2009) |
| GoldenPath | FOXN1 - 17q11.2 [CytoView hg19] FOXN1 - 17q11.2 [CytoView hg38] |
| ImmunoBase | ENSG00000109101 |
| Mapping of homologs : NCBI | FOXN1 [Mapview hg19] FOXN1 [Mapview hg38] |
| OMIM | 600838 601705 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF086453 AI288186 AK313878 Y11739 |
| RefSeq transcript (Entrez) | NM_001369369 NM_003593 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | FOXN1 |
| Cluster EST : Unigene | Hs.663679 [ NCBI ] |
| CGAP (NCI) | Hs.663679 |
| Alternative Splicing Gallery | ENSG00000109101 |
| Gene Expression | FOXN1 [ NCBI-GEO ] FOXN1 [ EBI - ARRAY_EXPRESS ]
FOXN1 [ SEEK ] FOXN1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | FOXN1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 8456 |
| GTEX Portal (Tissue expression) | FOXN1 |
| Human Protein Atlas | ENSG00000109101-FOXN1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O15353 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O15353 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O15353 |
| Splice isoforms : SwissVar | O15353 |
| PhosPhoSitePlus | O15353 |
| Domaine pattern : Prosite (Expaxy) | FORK_HEAD_2 (PS00658) FORK_HEAD_3 (PS50039) |
| Domains : Interpro (EBI) | Fork_head_dom TF_fork_head_CS_2 WH-like_DNA-bd_sf WH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | Forkhead (PF00250) |
| Domain families : Pfam (NCBI) | pfam00250 |
| Domain families : Smart (EMBL) | FH (SM00339) |
| Conserved Domain (NCBI) | FOXN1 |
| DMDM Disease mutations | 8456 |
| Blocks (Seattle) | FOXN1 |
| PDB (RSDB) | 5OCN 6EL8 |
| PDB Europe | 5OCN 6EL8 |
| PDB (PDBSum) | 5OCN 6EL8 |
| PDB (IMB) | 5OCN 6EL8 |
| Structural Biology KnowledgeBase | 5OCN 6EL8 |
| SCOP (Structural Classification of Proteins) | 5OCN 6EL8 |
| CATH (Classification of proteins structures) | 5OCN 6EL8 |
| Superfamily | O15353 |
| Human Protein Atlas [tissue] | ENSG00000109101-FOXN1 [tissue] |
| Peptide Atlas | O15353 |
| HPRD | 02907 |
| IPI | IPI00006163 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O15353 |
| IntAct (EBI) | O15353 |
| FunCoup | ENSG00000109101 |
| BioGRID | FOXN1 |
| STRING (EMBL) | FOXN1 |
| ZODIAC | FOXN1 |
| Ontologies - Pathways |
|---|
| QuickGO | O15353 |
| Ontology : AmiGO | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific hair follicle development T cell lineage commitment nucleus regulation of transcription by RNA polymerase II transcription by RNA polymerase II defense response epidermis development animal organ morphogenesis keratinocyte differentiation positive regulation of epithelial cell differentiation nail development T cell homeostasis sequence-specific DNA binding positive regulation of transcription by RNA polymerase II blood vessel morphogenesis epithelial cell proliferation positive regulation of hair follicle development lymphoid lineage cell migration into thymus thymus epithelium morphogenesis regulation of positive thymic T cell selection |
| Ontology : EGO-EBI | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific hair follicle development T cell lineage commitment nucleus regulation of transcription by RNA polymerase II transcription by RNA polymerase II defense response epidermis development animal organ morphogenesis keratinocyte differentiation positive regulation of epithelial cell differentiation nail development T cell homeostasis sequence-specific DNA binding positive regulation of transcription by RNA polymerase II blood vessel morphogenesis epithelial cell proliferation positive regulation of hair follicle development lymphoid lineage cell migration into thymus thymus epithelium morphogenesis regulation of positive thymic T cell selection |
| NDEx Network | FOXN1 |
| Atlas of Cancer Signalling Network | FOXN1 |
| Wikipedia pathways | FOXN1 |
| Orthology - Evolution |
|---|
| OrthoDB | 8456 |
| GeneTree (enSembl) | ENSG00000109101 |
| Phylogenetic Trees/Animal Genes : TreeFam | FOXN1 |
| HOGENOM | O15353 |
| Homologs : HomoloGene | FOXN1 |
| Homology/Alignments : Family Browser (UCSC) | FOXN1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | FOXN1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | FOXN1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | FOXN1 |
| dbVar | FOXN1 |
| ClinVar | FOXN1 |
| 1000_Genomes | FOXN1 |
| Exome Variant Server | FOXN1 |
| ExAC (Exome Aggregation Consortium) | ENSG00000109101 |
| GNOMAD Browser | ENSG00000109101 |
| Varsome Browser | FOXN1 |
| Genetic variants : HAPMAP | 8456 |
| Genomic Variants (DGV) | FOXN1 [DGVbeta] |
| DECIPHER | FOXN1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | FOXN1 |
| Mutations |
|---|
| ICGC Data Portal | FOXN1 |
| TCGA Data Portal | FOXN1 |
| Broad Tumor Portal | FOXN1 |
| OASIS Portal | FOXN1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | FOXN1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | FOXN1 |
| Mutations and Diseases : HGMD | FOXN1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | **PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database |
| BioMuta | search FOXN1 |
| DgiDB (Drug Gene Interaction Database) | FOXN1 |
| DoCM (Curated mutations) | FOXN1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | FOXN1 (select a term) |
| intoGen | FOXN1 |
| Cancer3D | FOXN1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 600838 601705 |
| Orphanet | 17819 |
| DisGeNET | FOXN1 |
| Medgen | FOXN1 |
| Genetic Testing Registry | FOXN1
|
| NextProt | O15353 [Medical] |
| TSGene | 8456 |
| GENETests | FOXN1 |
| Target Validation | FOXN1 |
| Huge Navigator |
FOXN1 [HugePedia] |
| snp3D : Map Gene to Disease | 8456 |
| BioCentury BCIQ | FOXN1 |
| ClinGen | FOXN1 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 8456 |
| Chemical/Pharm GKB Gene | PA37368 |
| Clinical trial | FOXN1 |
| Miscellaneous |
|---|
| canSAR (ICR) | FOXN1 (select the gene name) |
| DataMed Index | FOXN1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 23 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | FOXN1 |
| EVEX | FOXN1 |
| GoPubMed | FOXN1 |
| iHOP | FOXN1 |
