FOXP4 (forkhead box P4)

2007-04-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
hFKHLA
FUSION GENES

Other Information

Locus ID:

NCBI: 116113
MIM: 608924
HGNC: 20842
Ensembl: ENSG00000137166

Variants:

dbSNP: 116113
ClinVar: 116113
TCGA: ENSG00000137166
COSMIC: FOXP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137166ENST00000307972Q8IVH2
ENSG00000137166ENST00000373057Q8IVH2
ENSG00000137166ENST00000373060Q8IVH2
ENSG00000137166ENST00000373063Q8IVH2
ENSG00000137166ENST00000409208B7ZBM3
ENSG00000137166ENST00000451305A2A312
ENSG00000137166ENST00000670130A0A590UJX7

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384296642024Polymorphisms of IFN signaling genes and FOXP4 influence the severity of COVID-19.0
387407442024FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development.0
384296642024Polymorphisms of IFN signaling genes and FOXP4 influence the severity of COVID-19.0
387407442024FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development.0
360180672023FOXP4 promotes proliferation of human spermatogonial stem cells.3
363010212023Recurrent FOXP4 nonsense variant in two unrelated patients: Association with neurodevelopmental disease and congenital diaphragmatic hernia.0
360180672023FOXP4 promotes proliferation of human spermatogonial stem cells.3
363010212023Recurrent FOXP4 nonsense variant in two unrelated patients: Association with neurodevelopmental disease and congenital diaphragmatic hernia.0
356426652022Downregulation of microRNA‑423‑5p suppresses TGF‑β1‑induced EMT by targeting FOXP4 in airway fibrosis.2
358382332022FOXP4 inhibits squamous differentiation of atypical cells in cervical intraepithelial neoplasia via an ELF3-dependent pathway.3
356426652022Downregulation of microRNA‑423‑5p suppresses TGF‑β1‑induced EMT by targeting FOXP4 in airway fibrosis.2
358382332022FOXP4 inhibits squamous differentiation of atypical cells in cervical intraepithelial neoplasia via an ELF3-dependent pathway.3
331102672021Heterozygous variants that disturb the transcriptional repressor activity of FOXP4 cause a developmental disorder with speech/language delays and multiple congenital abnormalities.12
336498502021circ‑0000212 promotes cell proliferation of colorectal cancer by sponging miR‑491 and modulating FOXP4 expression.5
343847872021The forkhead box transcription factor FoxP4 regulates thermogenic programs in adipocytes.2

Citation

Dessen P

FOXP4 (forkhead box P4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47477/foxp4