FPGT (fucose-1-phosphate guanylyltransferase)

2014-11-01 Affiliation

Identity

HGNC

FPGT

LOCATION

1p31.1

LOCUSID

8790

ALIAS

GFPP

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8790
MIM: 603609
HGNC: 3825
Ensembl: ENSG00000254685

Variants:

dbSNP: 8790
ClinVar: 8790
TCGA: ENSG00000254685
COSMIC: FPGT

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000254685	ENST00000370894	O14772
ENSG00000254685	ENST00000370894	A0A0S2Z4P4
ENSG00000254685	ENST00000370898	O14772
ENSG00000254685	ENST00000467578	E9PMK0
ENSG00000254685	ENST00000472069	H0YDF0
ENSG00000254685	ENST00000482102	E9PMM4
ENSG00000254685	ENST00000529485	E9PK10
ENSG00000254685	ENST00000534056	O14772

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Fructose and mannose metabolism	KEGG	ko00051
Amino sugar and nucleotide sugar metabolism	KEGG	ko00520
Fructose and mannose metabolism	KEGG	hsa00051
Amino sugar and nucleotide sugar metabolism	KEGG	hsa00520
Metabolic pathways	KEGG	hsa01100
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Asparagine N-linked glycosylation	REACTOME	R-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	REACTOME	R-HSA-446193
Synthesis of substrates in N-glycan biosythesis	REACTOME	R-HSA-446219
GDP-fucose biosynthesis	REACTOME	R-HSA-6787639

References

Pubmed ID	Year	Title	Citations
16086588	2005	Substrate discrimination by the human GTP fucose pyrophosphorylase.	21
16185085	2005	Identification of catalytic amino acids in the human GTP fucose pyrophosphorylase active site.	16
16582493	2006	Purification, crystallization and preliminary X-ray characterization of the human GTP fucose pyrophosphorylase.	1

Citation

Dessen P

FPGT (fucose-1-phosphate guanylyltransferase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63579/fpgt