Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10023
MIM: 602503
HGNC: 3944
Ensembl: ENSG00000165879
Variants:
dbSNP: 10023
ClinVar: 10023
TCGA: ENSG00000165879
COSMIC: FRAT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165879 | ENST00000371021 | Q92837 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35059733 | 2022 | FRAT1 promotes the angiogenic properties of human glioblastoma cells via VEGFA. | 1 |
| 36153370 | 2022 | The miR-3648/FRAT1-FRAT2/c-Myc negative feedback loop modulates the metastasis and invasion of gastric cancer cells. | 6 |
| 35059733 | 2022 | FRAT1 promotes the angiogenic properties of human glioblastoma cells via VEGFA. | 1 |
| 36153370 | 2022 | The miR-3648/FRAT1-FRAT2/c-Myc negative feedback loop modulates the metastasis and invasion of gastric cancer cells. | 6 |
| 34319909 | 2021 | LncRNA CCAT1 promotes prostate cancer cells proliferation, migration, and invasion through regulation of miR-490-3p/FRAT1 axis. | 7 |
| 34319909 | 2021 | LncRNA CCAT1 promotes prostate cancer cells proliferation, migration, and invasion through regulation of miR-490-3p/FRAT1 axis. | 7 |
| 27599661 | 2016 | Frequently rearranged in advanced T‑cell lymphomas‑1 demonstrates oncogenic properties in prostate cancer. | 2 |
| 27666874 | 2016 | Knockdown of FRAT1 inhibits hypoxia-induced epithelial-to-mesenchymal transition via suppression of the Wnt/β-catenin pathway in hepatocellular carcinoma cells. | 7 |
| 27599661 | 2016 | Frequently rearranged in advanced T‑cell lymphomas‑1 demonstrates oncogenic properties in prostate cancer. | 2 |
| 27666874 | 2016 | Knockdown of FRAT1 inhibits hypoxia-induced epithelial-to-mesenchymal transition via suppression of the Wnt/β-catenin pathway in hepatocellular carcinoma cells. | 7 |
| 25387569 | 2015 | The clinical pathological significance of FRAT1 and ROR2 expression in cartilage tumors. | 4 |
| 25922553 | 2015 | Overexpression of FRAT1 is associated with malignant phenotype and poor prognosis in human gliomas. | 8 |
| 26178481 | 2015 | The clinical significance of FRAT1 and ABCG2 expression in pancreatic ductal adenocarcinoma. | 10 |
| 25387569 | 2015 | The clinical pathological significance of FRAT1 and ROR2 expression in cartilage tumors. | 4 |
| 25922553 | 2015 | Overexpression of FRAT1 is associated with malignant phenotype and poor prognosis in human gliomas. | 8 |
Citation
Dessen P
FRAT1 (FRAT regulator of WNT signaling pathway 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/464/frat1
