FRMD5 (FERM domain containing 5)

2012-12-01  

Identity

HGNC
LOCATION
15q15.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 84978
MIM: 616309
HGNC: 28214
Ensembl: ENSG00000171877

Variants:

dbSNP: 84978
ClinVar: 84978
TCGA: ENSG00000171877
COSMIC: FRMD5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171877ENST00000402883B5MC67
ENSG00000171877ENST00000417257Q7Z6J6
ENSG00000171877ENST00000421674F8WEJ8
ENSG00000171877ENST00000449926H0Y5N1
ENSG00000171877ENST00000451277F8WCI0
ENSG00000171877ENST00000458630H7C282
ENSG00000171877ENST00000484674H0YKW6
ENSG00000171877ENST00000558108H0YNI9
ENSG00000171877ENST00000618556A0A087WVP2
ENSG00000171877ENST00000636859A0A1B0GV18

Expression (GTEx)

0
5
10
15
20

References

Pubmed IDYearTitleCitations
228467082012FERM-containing protein FRMD5 is a p120-catenin interacting protein that regulates tumor progression.6
254486752014FERM domain-containing protein FRMD5 regulates cell motility via binding to integrin β5 subunit and ROCK1.6
283326152017Integrative variants, haplotypes and diplotypes of the CAPN3 and FRMD5 genes and several environmental exposures associate with serum lipid variables.4
281175512017Identification of FERM domain-containing protein 5 as a novel target of β-catenin/TCF7L2 complex.2
305830722019C-terminal truncated HBx protein activates caveolin-1/LRP6/β-catenin/FRMD5 axis in promoting hepatocarcinogenesis.2

Citation

Dessen P

FRMD5 (FERM domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53114/frmd5