FRMD8 (FERM domain containing 8)

2019-04-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
FKSG44,iTAP
FUSION GENES

Other Information

Locus ID:

NCBI: 83786
MIM: 618337
HGNC: 25462
Ensembl: ENSG00000126391

Variants:

dbSNP: 83786
ClinVar: 83786
TCGA: ENSG00000126391
COSMIC: FRMD8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126391ENST00000317568Q9BZ67
ENSG00000126391ENST00000355991Q9BZ67
ENSG00000126391ENST00000416776Q9BZ67
ENSG00000126391ENST00000525156E9PRA3
ENSG00000126391ENST00000526201E9PRP1
ENSG00000126391ENST00000531296Q8N4M4
ENSG00000126391ENST00000533782E9PS62

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
298973362018FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.8
298973332018iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.6

Citation

Dessen P

FRMD8 (FERM domain containing 8)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57929/frmd8