FSCN2 (fascin actin-bundling protein 2, retinal)

2008-08-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
RFSN,RP30

Other Information

Locus ID:

NCBI: 25794
MIM: 607643
HGNC: 3960
Ensembl: ENSG00000186765

Variants:

dbSNP: 25794
ClinVar: 25794
TCGA: ENSG00000186765
COSMIC: FSCN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186765ENST00000334850O14926
ENSG00000186765ENST00000417245O14926

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

References

Pubmed IDYearTitleCitations
244144192014Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization.20
192075542009Cortactin, fascin, and survivin expression associated with clinicopathological parameters in esophageal squamous cell carcinoma.14
172514462007The 208delG mutation in FSCN2 does not associate with retinal degeneration in Chinese individuals.12
204108082010Fascin expression predicts survival after potentially curative resection of node-positive colon cancer.10
146099212003Autosomal dominant macular degeneration associated with 208delG mutation in the FSCN2 gene.9
194734432009Effects of small interfering RNAs targeting Fascin on gene expression in oral cancer cells.7
219755522011The filopodium: a stable structure with highly regulated repetitive cycles of elongation and persistence depending on the actin cross-linker fascin.7
240705742013Serological investigation of the clinical significance of fascin in non-small-cell lung cancer.6
146615422003[Molecular genetic analysis for Japanese patients with autosomal dominant retinitis pigmentosa].5
162809782005Sequence variations in the retinal fascin FSCN2 gene in a Spanish population with autosomal dominant retinitis pigmentosa or macular degeneration.5

Citation

Dessen P

FSCN2 (fascin actin-bundling protein 2, retinal)

Atlas Genet Cytogenet Oncol Haematol. 2008-08-01

Online version: http://atlasgeneticsoncology.org/gene/50295/fscn2