Identity
HGNC
LOCATION
2p16.3
LOCUSID
ALIAS
FSHR1,FSHRO,LGR1,ODG1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2492
MIM: 136435
HGNC: 3969
Ensembl: ENSG00000170820
Variants:
dbSNP: 2492
ClinVar: 2492
TCGA: ENSG00000170820
COSMIC: FSHR
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170820 | ENST00000304421 | P23945 |
| ENSG00000170820 | ENST00000406846 | A0A1D5RMN4 |
| ENSG00000170820 | ENST00000419927 | F8WBM4 |
| ENSG00000170820 | ENST00000454032 | C9JDA1 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164746560 | thyrotropin alfa | Chemical | ClinicalAnnotation | associated | PK | PD | 21121812 |
| PA165108853 | Ovarian hyperstimulation syndrome | Disease | ClinicalAnnotation | associated | PK | PD | 21121812 |
| PA444618 | Infertility, Female | Disease | ClinicalAnnotation | associated | PK | PD | 21121812 |
| PA449693 | follitropin beta | Chemical | ClinicalAnnotation | associated | PK | PD | 21121812 |
| PA451835 | urofollitropin | Chemical | ClinicalAnnotation | associated | PK | PD | 21121812 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38664537 | 2024 | Prevalence of FSH-R Asn680Ser and Ala307Thr receptor polymorphism and their correlation with ART outcomes among infertile Indian-Asian women-a prospective cohort study. | 0 |
| 38664537 | 2024 | Prevalence of FSH-R Asn680Ser and Ala307Thr receptor polymorphism and their correlation with ART outcomes among infertile Indian-Asian women-a prospective cohort study. | 0 |
| 35680725 | 2023 | The Effect of the Allelics of Ser680Asn Polymorphisms of Follicle-Stimulating Hormone Receptor Gene in IVF/ICSI Cycles: a Systematic Review and Meta-analysis. | 2 |
| 36350975 | 2023 | Association of FSHR and DENND1A polymorphisms with polycystic ovary syndrome: a meta-analysis. | 1 |
| 36821034 | 2023 | Analyzing the Impact of FSHR Variants on Polycystic Ovary Syndrome-a Case-Control Study in Punjab. | 5 |
| 37130623 | 2023 | Association between sequence variants in the FSHR gene and reproductive outcomes following IVF in predicted normoresponders. | 0 |
| 37228156 | 2023 | Exploring the expression and potential function of follicle stimulating hormone receptor in extragonadal cells related to abdominal aortic aneurysm. | 0 |
| 37287186 | 2023 | Ala307Thr variation modulates FSHR structure and impairs its binding affinity for FSH: Implications in polycystic ovarian syndrome. | 0 |
| 37653412 | 2023 | Polymorphisms in FSHR modulating susceptibility to polycystic ovary syndrome: an updated meta-analysis. | 0 |
| 35680725 | 2023 | The Effect of the Allelics of Ser680Asn Polymorphisms of Follicle-Stimulating Hormone Receptor Gene in IVF/ICSI Cycles: a Systematic Review and Meta-analysis. | 2 |
| 36350975 | 2023 | Association of FSHR and DENND1A polymorphisms with polycystic ovary syndrome: a meta-analysis. | 1 |
| 36821034 | 2023 | Analyzing the Impact of FSHR Variants on Polycystic Ovary Syndrome-a Case-Control Study in Punjab. | 5 |
| 37130623 | 2023 | Association between sequence variants in the FSHR gene and reproductive outcomes following IVF in predicted normoresponders. | 0 |
| 37228156 | 2023 | Exploring the expression and potential function of follicle stimulating hormone receptor in extragonadal cells related to abdominal aortic aneurysm. | 0 |
| 37287186 | 2023 | Ala307Thr variation modulates FSHR structure and impairs its binding affinity for FSH: Implications in polycystic ovarian syndrome. | 0 |
Citation
Dessen P
FSHR (follicle stimulating hormone receptor)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/507/fshr
