FSIP1 (fibrous sheath interacting protein 1)

2014-03-01  

Identity

HGNC
FSIP1
LOCATION
15q14
LOCUSID
161835
ALIAS
HSD10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 161835
MIM: 615795
HGNC: 21674
Ensembl: ENSG00000150667

Variants:

dbSNP: 161835
ClinVar: 161835
TCGA: ENSG00000150667
COSMIC: FSIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150667ENST00000350221Q8NA03
ENSG00000150667ENST00000350221A0A024R9J2
ENSG00000150667ENST00000559547H0YNV9
ENSG00000150667ENST00000560769A0A2R8Y503
ENSG00000150667ENST00000642527A0A2R8YHB5

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443450AsthmaDiseaseClinicalAnnotationassociatedPD
PA448497aspirinChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
239058972013Elevated expression of cancer/testis antigen FSIP1 in ER-positive breast tumors.12
258260842015Expression and clinicopathological significance of FSIP1 in breast cancer.11
205132472010Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.8
205132472010Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.8
280862392017Elevated fibrous sheath interacting protein 1 levels are associated with poor prognosis in non-small cell lung cancer patients.7
286740222017FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.7
305099732018FSIP1 regulates autophagy in breast cancer.4
308144892019Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization.4
317139312020FSIP1 is correlated with estrogen receptor status and poor prognosis.0

Citation

Dessen P

FSIP1 (fibrous sheath interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53844/fsip1