FSTL1 (follistatin like 1)

2003-02-01  

Identity

HGNC
LOCATION
3q13.33
LOCUSID
ALIAS
FRP,FSL1,MIR198,OCC-1,OCC1,tsc36
FUSION GENES

Other Information

Locus ID:

NCBI: 11167
MIM: 605547
HGNC: 3972
Ensembl: ENSG00000163430

Variants:

dbSNP: 11167
ClinVar: 11167
TCGA: ENSG00000163430
COSMIC: FSTL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163430ENST00000295633Q12841
ENSG00000163430ENST00000424703Q12841
ENSG00000163430ENST00000469005C9J5G4
ENSG00000163430ENST00000480823H7C4W4

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by BMPREACTOMER-HSA-201451

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
263750052015Epicardial FSTL1 reconstitution regenerates the adult mammalian heart.122
187189032008Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism.104
233959582013'See-saw' expression of microRNA-198 and FSTL1 from a single transcript in wound healing.71
200806502010Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.46
191091542009Follistatin-like protein 1 promotes arthritis by up-regulating IFN-gamma.44
255840112015Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice.43
187967372009Tumor suppressor effect of follistatin-like 1 in ovarian and endometrial carcinogenesis: a differential expression and functional analysis.41
203472652010MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia.34
248381422014Follistatin-like protein 1 and its role in inflammation and inflammatory diseases.31
186176212008Expression of follistatin-related genes is altered in heart failure.30

Citation

Dessen P

FSTL1 (follistatin like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40644/fstl1