Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2512
MIM: 134790
HGNC: 3999
Ensembl: ENSG00000087086
Variants:
dbSNP: 2512
ClinVar: 2512
TCGA: ENSG00000087086
COSMIC: FTL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000087086 | ENST00000331825 | P02792 |
| ENSG00000087086 | ENST00000331825 | A0A384MDR3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37118836 | 2023 | Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain. | 6 |
| 37118836 | 2023 | Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain. | 6 |
| 36446230 | 2022 | Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling. | 4 |
| 36446230 | 2022 | Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling. | 4 |
| 33249617 | 2021 | Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity. | 7 |
| 33548513 | 2021 | A 3'-truncating FTL mutation associated with hypoferritinemia without neuroferritinopathy. | 0 |
| 33595184 | 2021 | Increasing ferritin predicts early death in adult hemophagocytic lymphohistiocytosis. | 9 |
| 33731140 | 2021 | Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC. | 5 |
| 33864445 | 2021 | Comprehensive analysis of ferritin subunits expression and positive correlations with tumor-associated macrophages and T regulatory cells infiltration in most solid tumors. | 20 |
| 34080727 | 2021 | Longitudinal CSF Iron Pathway Proteins in Posthemorrhagic Hydrocephalus: Associations with Ventricle Size and Neurodevelopmental Outcomes. | 13 |
| 34155536 | 2021 | Extracellular vesicles from thalassemia patients carry iron-containing ferritin and hemichrome that promote cardiac cell proliferation. | 7 |
| 34265052 | 2021 | CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles. | 37 |
| 34535730 | 2021 | Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells. | 12 |
| 34789084 | 2021 | Ferritin L-subunit gene mutation and hereditary hyperferritinaemia cataract syndrome (HHCS): a case report and literature review. | 1 |
| 33249617 | 2021 | Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity. | 7 |
Citation
Dessen P
FTL (ferritin light chain)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45708/ftl
