FTMT (ferritin mitochondrial)

2011-12-01 Affiliation

Identity

HGNC

FTMT

LOCATION

5q23.1

LOCUSID

94033

ALIAS

MTF

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 94033
MIM: 608847
HGNC: 17345
Ensembl: ENSG00000181867

Variants:

dbSNP: 94033
ClinVar: 94033
TCGA: ENSG00000181867
COSMIC: FTMT

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000181867	ENST00000321339	Q8N4E7

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Ferroptosis	KEGG	ko04216
Ferroptosis	KEGG	hsa04216

References

Pubmed ID	Year	Title	Citations
17459943	2007	Ferritin: a novel mechanism for delivery of iron to the brain and other organs.	55
12406866	2003	Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia.	51
18815198	2009	Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia.	49
16537925	2006	Hemin-mediated regulation of an antioxidant-responsive element of the human ferritin H gene and role of Ref-1 during erythroid differentiation of K562 cells.	43
11953424	2002	Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism.	40
15755449	2005	Unique iron binding and oxidation properties of human mitochondrial ferritin: a comparative analysis with Human H-chain ferritin.	29
18160053	2008	The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin.	22
19816198	2009	Mitochondrial ferritin in the substantia nigra in restless legs syndrome.	21
17565989	2007	PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element.	19
18325346	2008	Role and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stress.	18

Citation

Dessen P

FTMT (ferritin mitochondrial)

Atlas Genet Cytogenet Oncol Haematol. 2011-12-01

Online version: http://atlasgeneticsoncology.org/gene/52500/ftmt