FTSJ3 (FtsJ RNA 2-O-methyltransferase 3)

2014-11-01  

Identity

HGNC
FTSJ3
LOCATION
17q23.3
LOCUSID
117246
ALIAS
EPCS3,SPB1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 117246
MIM: 618411
HGNC: 17136
Ensembl: ENSG00000108592

Variants:

dbSNP: 117246
ClinVar: 117246
TCGA: ENSG00000108592
COSMIC: FTSJ3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108592ENST00000427159Q8IY81
ENSG00000108592ENST00000579569J3KS74
ENSG00000108592ENST00000579831J3KRY4
ENSG00000108592ENST00000580272J3KS36
ENSG00000108592ENST00000581209J3QSE2
ENSG00000108592ENST00000584193J3QR05
ENSG00000108592ENST00000584574J3QRS5
ENSG00000108592ENST00000585145J3QKT6

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
306269732019FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensing.24
221950172011The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing.10
225408642012Proteomic characterization of the human FTSJ3 preribosomal complexes.6

Citation

Dessen P

FTSJ3 (FtsJ RNA 2-O-methyltransferase 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63624/ftsj3