Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2527
MIM: 136835
HGNC: 4016
Ensembl: ENSG00000130383
Variants:
dbSNP: 2527
ClinVar: 2527
TCGA: ENSG00000130383
COSMIC: FUT5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130383 | ENST00000252675 | Q11128 |
| ENSG00000130383 | ENST00000588525 | K7ENC0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Glycosphingolipid biosynthesis - lacto and neolacto series | KEGG | ko00601 |
| Glycosphingolipid biosynthesis - lacto and neolacto series | KEGG | hsa00601 |
| Metabolic pathways | KEGG | hsa01100 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30808544 | 2019 | Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines. | 7 |
| 30808544 | 2019 | Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines. | 7 |
| 28771224 | 2017 | miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway. | 61 |
| 28771224 | 2017 | miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway. | 61 |
| 22619806 | 2012 | [Distribution specificity of human fucosyltransferase 5 and its expression and localization in spermatids]. | 0 |
| 22619806 | 2012 | [Distribution specificity of human fucosyltransferase 5 and its expression and localization in spermatids]. | 0 |
| 21978830 | 2011 | Down-regulation of FUT3 and FUT5 by shRNA alters Lewis antigens expression and reduces the adhesion capacities of gastric cancer cells. | 22 |
| 21978830 | 2011 | Down-regulation of FUT3 and FUT5 by shRNA alters Lewis antigens expression and reduces the adhesion capacities of gastric cancer cells. | 22 |
| 20677162 | 2010 | [The genetic diversity in the full coding region of human FUT5 gene in a Chinese Han population]. | 0 |
| 20677162 | 2010 | [The genetic diversity in the full coding region of human FUT5 gene in a Chinese Han population]. | 0 |
| 19349624 | 2009 | Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells. | 7 |
| 19349624 | 2009 | Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells. | 7 |
| 17148576 | 2007 | Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding. | 15 |
| 17148576 | 2007 | Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding. | 15 |
| 14601054 | 2003 | Gene transfer of alpha1,3-fucosyltransferase increases tumor growth of the PC-3 human prostate cancer cell line through enhanced adhesion to prostatic stromal cells. | 12 |
Citation
Dessen P
FUT5 (fucosyltransferase 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45680/fut5
