Identity
HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
Fz2,OMOD2,fz-2,fzE2,hFz2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2535
MIM: 600667
HGNC: 4040
Ensembl: ENSG00000180340
Variants:
dbSNP: 2535
ClinVar: 2535
TCGA: ENSG00000180340
COSMIC: FZD2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000180340 | ENST00000315323 | Q14332 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38967226 | 2024 | Craniofacial studies in chicken embryos confirm the pathogenicity of human FZD2 variants associated with Robinow syndrome. | 1 |
| 38967226 | 2024 | Craniofacial studies in chicken embryos confirm the pathogenicity of human FZD2 variants associated with Robinow syndrome. | 1 |
| 34986855 | 2022 | Integrated weighted gene coexpression network analysis identifies Frizzled 2 (FZD2) as a key gene in invasive malignant pleomorphic adenoma. | 3 |
| 34986855 | 2022 | Integrated weighted gene coexpression network analysis identifies Frizzled 2 (FZD2) as a key gene in invasive malignant pleomorphic adenoma. | 3 |
| 30677195 | 2019 | Frizzled 2-induced epithelial-mesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinoma. | 26 |
| 30924074 | 2019 | Wnt Signaling Alterations in the Human Spinal Cord of Amyotrophic Lateral Sclerosis Cases: Spotlight on Fz2 and Wnt5a. | 20 |
| 31595151 | 2019 | FZD2 regulates cell proliferation and invasion in tongue squamous cell carcinoma. | 9 |
| 30677195 | 2019 | Frizzled 2-induced epithelial-mesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinoma. | 26 |
| 30924074 | 2019 | Wnt Signaling Alterations in the Human Spinal Cord of Amyotrophic Lateral Sclerosis Cases: Spotlight on Fz2 and Wnt5a. | 20 |
| 31595151 | 2019 | FZD2 regulates cell proliferation and invasion in tongue squamous cell carcinoma. | 9 |
| 29383834 | 2018 | Nonsense mutations in FZD2 cause autosomal-dominant omodysplasia: Robinow syndrome-like phenotypes. | 15 |
| 29748286 | 2018 | Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B. | 74 |
| 29383834 | 2018 | Nonsense mutations in FZD2 cause autosomal-dominant omodysplasia: Robinow syndrome-like phenotypes. | 15 |
| 29748286 | 2018 | Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B. | 74 |
| 28350091 | 2017 | Clinical implication of Frizzled 2 expression and its association with epithelial-to-mesenchymal transition in hepatocellular carcinoma. | 12 |
Citation
Dessen P
FZD2 (frizzled class receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-04-01
Online version: http://atlasgeneticsoncology.org/gene/50090/fzd2
