Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FZR1 (fizzy/cell division cycle 20 related 1 (Drosophila))

Identity

Other namesCDC20C
CDH1
FZR
FZR2
HCDH
HCDH1
HGNC (Hugo) FZR1
LocusID (NCBI) 51343
Location 19p13.3
Location_base_pair Starts at 3522954 and ends at 3536755 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FZR1   24824
Entrez_Gene (NCBI)FZR1  51343  fizzy/cell division cycle 20 related 1 (Drosophila)
Cards
GeneCards (Weizmann)FZR1
Ensembl (Hinxton)ENSG00000105325 [Gene_View]  chr19:3522954-3536755 [Contig_View]  FZR1 [Vega]
AceView (NCBI)FZR1
Genatlas (Paris)FZR1
SOURCE (Stanford)NM_001136197 NM_001136198 NM_016263
Genomic and cartography
GoldenPath (UCSC)FZR1  -  19p13.3   chr19:3522954-3536755 +  19p13.3   [Description]    (hg19-Feb_2009)
EnsemblFZR1 - 19p13.3 [CytoView]
Mapping of homologs : NCBIFZR1 [Mapview]
OMIM603619   
Gene and transcription
Genbank (Entrez)AB013462 AB013463 AB033068 AF080397 AF083810
RefSeq transcript (SRS)NM_001136197 NM_001136198 NM_016263
RefSeq transcript (Entrez)NM_001136197 NM_001136198 NM_016263
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NT_011255 NW_001838476 NW_004078096
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011255 NW_001838476 NW_004078096
Consensus coding sequences : CCDS (NCBI)FZR1
Cluster EST : UnigeneHs.413133 [ SRS ] Hs.413133 [ NCBI ]
CGAP (NCI)Hs.413133
Alternative Splicing : Fast-db (Paris)GSHG0014465
Alternative Splicing GalleryENSG00000105325
Gene ExpressionFZR1 [ NCBI-GEO ]   FZR1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UM11 (SRS) Q9UM11 (Uniprot)
NextProtQ9UM11
With graphics : InterProQ9UM11
Splice isoforms : SwissVarQ9UM11(Swissvar)
Domaine pattern : Prosite (SRS)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (SRS)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Related proteins : CluSTrQ9UM11
Domain families : Pfam (SRS)WD40 (PF00400)   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
DMDM51343
Blocks (Seattle)Q9UM11
Human Protein AtlasENSG00000105325
HPRD04687
IPIIPI00383919   IPI00099464   IPI00043958   
Protein Interaction databases
DIP (DOE-UCLA)Q9UM11
IntAct (EBI)Q9UM11
FunCoupENSG00000105325
REACTOMEFZR1
Protein Interaction Database51343
BioGRIDFZR1
InParanoidQ9UM11
Interologous Interaction database Q9UM11
IntegromeDBFZR1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FZR1
SNP (GeneSNP Utah)FZR1
SNP : HGBaseFZR1
Genetic variants : HAPMAPFZR1
Somatic Mutations in Cancer : COSMICFZR1 
CONAN: Copy Number AnalysisFZR1 
Mutations and Diseases : HGMDFZR1
OMIM603619   
GENETests603619   
Disease Genetic AssociationFZR1
Huge Navigator FZR1 [HugePedia]  FZR1 [HugeCancerGEM]
Genomic VariantsFZR1  FZR1 [DGVbeta]
snp3D : Map Gene to Disease51343
General knowledge
Homologs : HomoloGeneFZR1
Homology/Alignments : Family Browser (UCSC)FZR1
Phylogenetic Trees/Animal Genes : TreeFamFZR1
Chemical/Protein Interactions : CTD51343
Chemical/Pharm GKB GenePA134896003
Clinical trialFZR1
Cancer Resource (Charite)ENSG00000105325
Ontology : AmiGOS phase of mitotic cell cycle  mitotic cell cycle  protein binding  nucleus  nucleoplasm  anaphase-promoting complex  nucleolus  cytosol  DNA repair  mitosis  positive regulation of cell proliferation  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  G2/M transition DNA damage checkpoint  nuclear membrane  regulation of meiosis  positive regulation of protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  activation of anaphase-promoting complex activity  lens fiber cell differentiation  protein K11-linked ubiquitination  negative regulation of cell aging  
Ontology : EGO-EBIS phase of mitotic cell cycle  mitotic cell cycle  protein binding  nucleus  nucleoplasm  anaphase-promoting complex  nucleolus  cytosol  DNA repair  mitosis  positive regulation of cell proliferation  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  G2/M transition DNA damage checkpoint  nuclear membrane  regulation of meiosis  positive regulation of protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  activation of anaphase-promoting complex activity  lens fiber cell differentiation  protein K11-linked ubiquitination  negative regulation of cell aging  
Pathways : KEGGCell cycleUbiquitin mediated proteolysis
Other databases
Probes
Litterature
PubMed95 Pubmed reference(s) in Entrez
PubGeneFZR1
iHOPFZR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:42:12 CEST 2013
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