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GABRQ (gamma-aminobutyric acid type A receptor subunit theta)

Identity

Alias_namesgamma-aminobutyric acid (GABA) receptor, theta
gamma-aminobutyric acid (GABA) A receptor, theta
Alias_symbol (synonym)THETA
Other alias
HGNC (Hugo) GABRQ
LocusID (NCBI) 55879
Atlas_Id 52936
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 152637895 and ends at 152657542 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GABRQ   14454
Cards
Entrez_Gene (NCBI)GABRQ  55879  gamma-aminobutyric acid type A receptor subunit theta
AliasesTHETA
GeneCards (Weizmann)GABRQ
Ensembl hg19 (Hinxton)ENSG00000268089 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000268089 [Gene_View]  ENSG00000268089 [Sequence]  chrX:152637895-152657542 [Contig_View]  GABRQ [Vega]
ICGC DataPortalENSG00000268089
TCGA cBioPortalGABRQ
AceView (NCBI)GABRQ
Genatlas (Paris)GABRQ
WikiGenes55879
SOURCE (Princeton)GABRQ
Genetics Home Reference (NIH)GABRQ
Genomic and cartography
GoldenPath hg38 (UCSC)GABRQ  -     chrX:152637895-152657542 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GABRQ  -     Xq28   [Description]    (hg19-Feb_2009)
GoldenPathGABRQ - Xq28 [CytoView hg19]  GABRQ - Xq28 [CytoView hg38]
Genome Data Viewer NCBIGABRQ [Mapview hg19]  
OMIM300349   
Gene and transcription
Genbank (Entrez)AF144648 AF189259 BC109210 BC109211 U47334
RefSeq transcript (Entrez)NM_018558
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GABRQ
Alternative Splicing GalleryENSG00000268089
Gene ExpressionGABRQ [ NCBI-GEO ]   GABRQ [ EBI - ARRAY_EXPRESS ]   GABRQ [ SEEK ]   GABRQ [ MEM ]
Gene Expression Viewer (FireBrowse)GABRQ [ Firebrowse - Broad ]
GenevisibleExpression of GABRQ in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55879
GTEX Portal (Tissue expression)GABRQ
Human Protein AtlasENSG00000268089-GABRQ [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UN88   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UN88  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UN88
Splice isoforms : SwissVarQ9UN88
PhosPhoSitePlusQ9UN88
Domaine pattern : Prosite (Expaxy)NEUROTR_ION_CHANNEL (PS00236)   
Domains : Interpro (EBI)GABAA/Glycine_rcpt    GABAAt_rcpt    Neur_chan_lig-bd    Neur_chan_lig-bd_sf    Neur_channel    Neuro-gated_channel_TM_sf    Neurotrans-gated_channel_TM    Neurotransmitter_ion_chnl_CS   
Domain families : Pfam (Sanger)Neur_chan_LBD (PF02931)    Neur_chan_memb (PF02932)   
Domain families : Pfam (NCBI)pfam02931    pfam02932   
Conserved Domain (NCBI)GABRQ
DMDM Disease mutations55879
SuperfamilyQ9UN88
Human Protein Atlas [tissue]ENSG00000268089-GABRQ [tissue]
Peptide AtlasQ9UN88
HPRD02284
IPIIPI00297913   IPI00333641   IPI00386067   
Protein Interaction databases
DIP (DOE-UCLA)Q9UN88
IntAct (EBI)Q9UN88
FunCoupENSG00000268089
BioGRIDGABRQ
STRING (EMBL)GABRQ
ZODIACGABRQ
Ontologies - Pathways
QuickGOQ9UN88
Ontology : AmiGOtransmembrane signaling receptor activity  GABA-A receptor activity  GABA-A receptor activity  extracellular ligand-gated ion channel activity  chloride channel activity  chloride channel activity  neurotransmitter transporter activity  plasma membrane  integral component of plasma membrane  neurotransmitter transport  signal transduction  chemical synaptic transmission  neurotransmitter receptor activity  ion transmembrane transport  chloride channel complex  regulation of membrane potential  neuron projection  receptor complex  synapse  postsynaptic membrane  nervous system process  chloride transmembrane transport  chloride transmembrane transport  GABA-A receptor complex  
Ontology : EGO-EBItransmembrane signaling receptor activity  GABA-A receptor activity  GABA-A receptor activity  extracellular ligand-gated ion channel activity  chloride channel activity  chloride channel activity  neurotransmitter transporter activity  plasma membrane  integral component of plasma membrane  neurotransmitter transport  signal transduction  chemical synaptic transmission  neurotransmitter receptor activity  ion transmembrane transport  chloride channel complex  regulation of membrane potential  neuron projection  receptor complex  synapse  postsynaptic membrane  nervous system process  chloride transmembrane transport  chloride transmembrane transport  GABA-A receptor complex  
Pathways : KEGGNeuroactive ligand-receptor interaction    Retrograde endocannabinoid signaling    GABAergic synapse    Morphine addiction    Nicotine addiction   
NDEx NetworkGABRQ
Atlas of Cancer Signalling NetworkGABRQ
Wikipedia pathwaysGABRQ
Orthology - Evolution
OrthoDB55879
GeneTree (enSembl)ENSG00000268089
Phylogenetic Trees/Animal Genes : TreeFamGABRQ
HOGENOMQ9UN88
Homologs : HomoloGeneGABRQ
Homology/Alignments : Family Browser (UCSC)GABRQ
Gene fusions - Rearrangements
Fusion : QuiverGABRQ
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGABRQ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GABRQ
dbVarGABRQ
ClinVarGABRQ
1000_GenomesGABRQ 
Exome Variant ServerGABRQ
GNOMAD BrowserENSG00000268089
Varsome BrowserGABRQ
Genetic variants : HAPMAP55879
Genomic Variants (DGV)GABRQ [DGVbeta]
DECIPHERGABRQ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGABRQ 
Mutations
ICGC Data PortalGABRQ 
TCGA Data PortalGABRQ 
Broad Tumor PortalGABRQ
OASIS PortalGABRQ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGABRQ  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGABRQ
Mutations and Diseases : HGMDGABRQ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutaselect GABRQ
DgiDB (Drug Gene Interaction Database)GABRQ
DoCM (Curated mutations)GABRQ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GABRQ (select a term)
intoGenGABRQ
Cancer3DGABRQ (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300349   
Orphanet
DisGeNETGABRQ
MedgenGABRQ
Genetic Testing Registry GABRQ
NextProtQ9UN88 [Medical]
TSGene55879
GENETestsGABRQ
Open Targets GeneticsENSG00000268089  [validation]
snp3D : Map Gene to Disease55879
BioCentury BCIQGABRQ
ClinGenGABRQ
Clinical trials, drugs, therapy
Protein Interactions : CTD55879
Pharm GKB GenePA28504
Clinical trialGABRQ
Miscellaneous
canSAR (ICR)GABRQ (select the gene name)
HarmonizomeGABRQ
DataMed IndexGABRQ
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGABRQ
EVEXGABRQ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 11 19:49:47 CEST 2020

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