GAL3ST4 (galactose-3-O-sulfotransferase 4)

2014-11-01  

Identity

HGNC
GAL3ST4
LOCATION
7q22.1
LOCUSID
79690
ALIAS
GAL3ST-4

Other Information

Locus ID:

NCBI: 79690
MIM: 608235
HGNC: 24145
Ensembl: ENSG00000197093

Variants:

dbSNP: 79690
ClinVar: 79690
TCGA: ENSG00000197093
COSMIC: GAL3ST4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197093ENST00000360039Q96RP7
ENSG00000197093ENST00000411994C9IZ77
ENSG00000197093ENST00000413800Q96RP7
ENSG00000197093ENST00000423751C9IZ77
ENSG00000197093ENST00000460995A0A0J9YYD8
ENSG00000197093ENST00000482469A0A0J9YVN4
ENSG00000197093ENST00000498000A0A0J9YXX0

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
259540322015Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice.24
231477952012Evidence for GAL3ST4 mutation as the potential cause of pectus excavatum.5
147018682004Identification of physiologically relevant substrates for cloned Gal: 3-O-sulfotransferases (Gal3STs): distinct high affinity of Gal3ST-2 and LS180 sulfotransferase for the globo H backbone, Gal3ST-3 for N-glycan multiterminal Galbeta1, 4GlcNAcbeta units and 6-sulfoGalbeta1, 4GlcNAcbeta, and Gal3ST-4 for the mucin core-2 trisaccharide.3
291806612017Identification of novel genetic loci GAL3ST4 and CHGB involved in susceptibility to leprosy.1

Citation

Dessen P

GAL3ST4 (galactose-3-O-sulfotransferase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63678/gal3st4